iPTMnet Report for P43378 (PTPN9)
Protein Information
| UniProt AC / UniProt ID | P43378 / PTN9_HUMAN |
| Protein Name | Tyrosine-protein phosphatase non-receptor type 9 |
| Gene Name | Name: PTPN9 |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P43378 |
| PRO Name | tyrosine-protein phosphatase non-receptor type 9 (human) |
| Definition | A tyrosine-protein phosphatase non-receptor type 9 that is encoded in the genome of human. |
| Short Label | hPTPN9 |
| Category | organism-gene |
P43378 (PTPN9) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| M1 | Acetylation | score1 | UniProt | 19413330 | ||
| K79 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S89 | Phosphorylation | score0 | HPRD | 20068231 | ||
| T97 | Phosphorylation | score0 | HPRD | 20068231 | ||
| Y133 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K170 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K176 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K185 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K218 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K300 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y304 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y307 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T318 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S322 | Phosphorylation | score2 | HPRD phospho.ELM | 18669648 | ||
| S324 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K330 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K367 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T375 | Phosphorylation | score0 | HPRD | 20068231 | ||
| Y442 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K444 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K503 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S557 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y565 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S592 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S89 | Y89 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| K170 | E170 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic ] | |
| T318 | I318 | Biomuta | DOID:4159 / skin cancer [ cosmic ] |
DAG View