iPTMnet Report for P43351 (RAD52)
Protein Information
UniProt AC / UniProt ID | P43351 / RAD52_HUMAN |
Protein Name | DNA repair protein RAD52 homolog |
Gene Name | Name: RAD52 |
Organism | Homo sapiens (Human) |
PRO ID | PR:P43351 |
PRO Name | DNA repair protein RAD52 homolog (human) |
Definition | A DNA repair protein RAD52 homolog that is encoded in the genome of human. |
Short Label | hRAD52 |
Category | organism-gene |
P43351 (RAD52) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S2 | Phosphorylation | score1 | PhosphoSitePlus | |||
K41 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y104 | Phosphorylation | P00519 (ABL1) , A0A173G4P4 (Abl fusion) , A9UF07 (BCR/ABL fusion) | score4 | neXtProt phospho.ELM PhosphoSitePlus RLIMS-P Signor UniProt | 12379650, 14757045, 32093728, ... | |
S129 | Phosphorylation | score1 | PhosphoSitePlus | |||
K133 | Acetylation | score1 | PhosphoSitePlus | |||
K135 | Ubiquitination | score1 | PhosphoSitePlus | |||
S138 | Phosphorylation | score1 | PhosphoSitePlus | |||
K141 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y171 | Phosphorylation | score1 | PhosphoSitePlus | |||
S174 | Phosphorylation | score1 | PhosphoSitePlus | |||
K177 | Acetylation | score1 | PhosphoSitePlus | |||
K177 | Ubiquitination | score1 | PhosphoSitePlus | |||
K190 | Acetylation | score1 | PhosphoSitePlus | |||
K192 | Acetylation | score1 | PhosphoSitePlus | |||
S199 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18691976 | ||
Y205 | Phosphorylation | score1 | PhosphoSitePlus | |||
S207 | Phosphorylation | score1 | PhosphoSitePlus | |||
T223 | Phosphorylation | score1 | PhosphoSitePlus | |||
S224 | Phosphorylation | score1 | PhosphoSitePlus | |||
S251 | Phosphorylation | score1 | PhosphoSitePlus | |||
K262 | Acetylation | score1 | PhosphoSitePlus | |||
K274 | Acetylation | score1 | PhosphoSitePlus | |||
T281 | Phosphorylation | score1 | PhosphoSitePlus | |||
K286 | Acetylation | score1 | PhosphoSitePlus | |||
S287 | Phosphorylation | score1 | PhosphoSitePlus | |||
S299 | Phosphorylation | score1 | PhosphoSitePlus | |||
T303 | Phosphorylation | score1 | PhosphoSitePlus | |||
T318 | Phosphorylation | score2 | phospho.ELM PhosphoSitePlus UniProt | 17525332 | ||
K323 | Acetylation | score1 | PhosphoSitePlus | |||
T335 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18691976 | ||
K344 | Acetylation | score1 | PhosphoSitePlus | |||
S385 | Phosphorylation | score1 | IEDB | 35494241 | ||
T397 | Phosphorylation | score1 | PhosphoSitePlus | |||
K406 | Acetylation | score1 | PhosphoSitePlus | |||
K411 | Sumoylation | score2 | PRO PhosphoSitePlus | |||
K412 | Acetylation | score1 | PhosphoSitePlus | |||
K412 | Sumoylation | score2 | PRO PhosphoSitePlus | |||
K414 | Acetylation | score1 | PhosphoSitePlus | |||
K414 | Sumoylation | score2 | PRO PhosphoSitePlus |
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
S2 | Phosphorylation | score0 | HPRD | 18691976 | ||
Y104 | Phosphorylation | P00519 (ABL1) | score1 | HPRD | 12379650 | |
Y171 | Phosphorylation | score0 | HPRD | 19664995 | ||
S174 | Phosphorylation | score0 | HPRD | 19664995 | ||
S199 | Phosphorylation | score0 | HPRD | 18691976 | ||
T318 | Phosphorylation | score0 | HPRD | 17525332 | ||
T335 | Phosphorylation | score0 | HPRD | 18691976 |
Proteoforms
PRO ID (Short Label) | Sites | PTM Enzyme | Source | PMID | |
---|---|---|---|---|---|
PR:000048995 (hRAD52/Sumo:1) | suK411,suK412,suK414 | PRO |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K135 | E135 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
K192 | N192 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
S287 | G287 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] |