iPTMnet Report for P43304 (GPD2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P43304 / GPDM_HUMAN
Protein Name Glycerol-3-phosphate dehydrogenase, mitochondrial precursor
Gene Name Name: GPD2
Organism Homo sapiens (Human)

PRO ID PR:P43304
DAG View
PRO Name glycerol-3-phosphate dehydrogenase, mitochondrial (human)
Definition A glycerol-3-phosphate dehydrogenase, mitochondrial that is encoded in the genome of human.
Short Label hGPD2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P43304 (GPD2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K33 Acetylation PhosphoSitePlus
K41 Acetylation PhosphoSitePlus
S47 Phosphorylation PhosphoSitePlus
T67 O-Glycosylation GlyGen 23301498, 35132862, 28510447, ...35083852, 29351928
T80 O-Glycosylation GlyGen 23301498, 35132862, 28510447, ...35083852, 29351928
K94 Ubiquitination PhosphoSitePlus
S104 Phosphorylation PhosphoSitePlus
S105 Phosphorylation PhosphoSitePlus
K113 Ubiquitination PhosphoSitePlus
Y121 Phosphorylation PhosphoSitePlus
K128 Ubiquitination PhosphoSitePlus
K138 Ubiquitination PhosphoSitePlus
K190 Methylation PhosphoSitePlus
K197 Ubiquitination PhosphoSitePlus
Y218 Phosphorylation PhosphoSitePlus
Y246 Phosphorylation PhosphoSitePlus
K271 Ubiquitination PhosphoSitePlus
T275 Phosphorylation PhosphoSitePlus
K284 Ubiquitination PhosphoSitePlus
T290 Phosphorylation PhosphoSitePlus
T294 Phosphorylation PhosphoSitePlus
S296 Phosphorylation PhosphoSitePlus
T355 Phosphorylation PhosphoSitePlus
T357 Phosphorylation PhosphoSitePlus
T359 Phosphorylation PhosphoSitePlus
T362 Phosphorylation PhosphoSitePlus
S384 Phosphorylation PhosphoSitePlus
K409 Ubiquitination PhosphoSitePlus
K453 Ubiquitination PhosphoSitePlus
K458 Ubiquitination PhosphoSitePlus
S476 Phosphorylation PhosphoSitePlus
Y487 Phosphorylation PhosphoSitePlus
K504 Ubiquitination PhosphoSitePlus
K510 Ubiquitination PhosphoSitePlus
S513 Phosphorylation PhosphoSitePlus
T515 Phosphorylation PhosphoSitePlus
Y532 Phosphorylation PhosphoSitePlus
Y544 Phosphorylation PhosphoSitePlus
T547 Phosphorylation PhosphoSitePlus
S553 Phosphorylation PhosphoSitePlus
Y586 Phosphorylation PhosphoSitePlus
Y600 Phosphorylation PhosphoSitePlus
Y601 Phosphorylation PhosphoSitePlus
Y605 Phosphorylation PhosphoSitePlus
S619 Phosphorylation PhosphoSitePlus
S623 Phosphorylation PhosphoSitePlus
K634 Acetylation PhosphoSitePlus
K634 Ubiquitination PhosphoSitePlus
T644 Phosphorylation IEDB 35494241
S723 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S104 L104 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
Y218 C218 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y246 * Biomuta DOID:1324 / lung cancer [ cosmic ]
T290 M290 Biomuta DOID:1319 / brain cancer [ cosmic ]
T294 M294 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S296 Y296 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S296 F296 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K453 Q453 Biomuta DOID:1324 / lung cancer [ cosmic ]
S476 R476 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K510 R510 Biomuta DOID:363 / uterine cancer [ icgc ]
S513 N513 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
T515 A515 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S553 L553 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
Y601 S601 Biomuta DOID:4159 / skin cancer [ cosmic ]