iPTMnet Report for P43268 (ETV4)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P43268 / ETV4_HUMAN
Protein Name ETS translocation variant 4
Gene Name Name: ETV4
Synonyms:E1AF,PEA3;
Organism Homo sapiens (Human)

PRO ID PR:P43268
DAG View
PRO Name ETS translocation variant 4 (human)
Definition An ETS translocation variant 4 that is encoded in the genome of human.
Short Label hETV4
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P43268 (ETV4) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S73 Phosphorylation PhosphoSitePlus   RLIMS-P 28373072
K96 Sumoylation PhosphoSitePlus
S101 Phosphorylation PhosphoSitePlus   UniProt 19307308
S140 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
S149 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
K226 Sumoylation PhosphoSitePlus
K260 Sumoylation PhosphoSitePlus
K322 Sumoylation PhosphoSitePlus
Y392 Phosphorylation PhosphoSitePlus
S396 Phosphorylation Q15831 (STK11) neXtProt 16912160
Y416 Phosphorylation PhosphoSitePlus
K441 Sumoylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S140 Phosphorylation HPRD 18669648, 20068231
S149 Phosphorylation HPRD 18669648, 20068231


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P43268 (ETV4) S73 Q8NHY2 (COP1) inhibited_association eFIP 28373072


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S73 N73 Biomuta DOID:4159 / skin cancer [ cosmic ]