iPTMnet Report for P43155 (CRAT)
Protein Information
| UniProt AC / UniProt ID | P43155 / CACP_HUMAN |
| Protein Name | Carnitine O-acetyltransferase |
| Gene Name | Name: CRAT Synonyms:CAT1; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P43155 |
| PRO Name | carnitine O-acetyltransferase (human) |
| Definition | A carnitine O-acetyltransferase that is encoded in the genome of human. |
| Short Label | hCRAT |
| Category | organism-gene |
P43155 (CRAT) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| K29 | Methylation | score1 | PhosphoSitePlus | |||
| S59 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y107 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y110 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y117 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K186 | Acetylation | score1 | PhosphoSitePlus | |||
| K195 | Acetylation | score1 | PhosphoSitePlus | |||
| T201 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N238 | N-Glycosylation | score1 | GlyGen | 29741879 | ||
| K261 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
| K268 | Acetylation | score2 | PhosphoSitePlus UniProt | 19608861 | ||
| K379 | Acetylation | score1 | PhosphoSitePlus | |||
| K380 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T467 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S472 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S485 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N586 | N-Glycosylation | score1 | GlyGen | 29671580 | ||
| Y606 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K609 | Acetylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S59 | N59 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] | |
| T201 | M201 | Biomuta | DOID:10534 / stomach cancer [ cosmic ] | |
| T201 | S201 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| K261 | N261 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| K380 | N380 | Biomuta | DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| T467 | N467 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
| S472 | Y472 | Biomuta | DOID:1324 / lung cancer [ cosmic ] | |
| S485 | F485 | Biomuta | [ cosmic ] | |
| Y606 | * | Biomuta | DOID:3571 / liver cancer [ cosmic ] |
DAG View