iPTMnet Report for P43003 (SLC1A3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P43003 / EAA1_HUMAN
Protein Name Excitatory amino acid transporter 1
Gene Name Name: SLC1A3
Synonyms:EAAT1;
Organism Homo sapiens (Human)

PRO ID PR:P43003
DAG View
PRO Name excitatory amino acid transporter 1 (human)
Definition An excitatory amino acid transporter 1 that is encoded in the genome of human.
Short Label hSLC1A3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P43003 (SLC1A3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T2 Phosphorylation PhosphoSitePlus
K3 Ubiquitination PhosphoSitePlus
S4 Phosphorylation PhosphoSitePlus
K10 Ubiquitination PhosphoSitePlus
T26 Phosphorylation PhosphoSitePlus
K31 Ubiquitination PhosphoSitePlus
K32 Ubiquitination PhosphoSitePlus
T37 Phosphorylation PhosphoSitePlus
K38 Acetylation PhosphoSitePlus
K38 Ubiquitination PhosphoSitePlus
S82 Phosphorylation PhosphoSitePlus
K191 Ubiquitination PhosphoSitePlus
K384 Ubiquitination PhosphoSitePlus
S512 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
K520 Ubiquitination PhosphoSitePlus
K521 Ubiquitination PhosphoSitePlus
Y523 Phosphorylation PhosphoSitePlus
K534 Ubiquitination PhosphoSitePlus
K541 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T482 Phosphorylation O00141 (SGK1) HPRD 12911626
S512 Phosphorylation HPRD 18669648, 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K31 N31 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ] DOID:9253 / gastrointestinal stromal tumor [ cosmic ]
T37 A37 Biomuta DOID:9256 / colorectal cancer [ cosmic ]