iPTMnet Report for P42785 (PRCP)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P42785 / PCP_HUMAN
Protein Name Lysosomal Pro-X carboxypeptidase precursor
Gene Name Name: PRCP
Synonyms:PCP;
Organism Homo sapiens (Human)

PRO ID PR:P42785
DAG View
PRO Name lysosomal Pro-X carboxypeptidase (human)
Definition A lysosomal Pro-X carboxypeptidase that is encoded in the genome of human.
Short Label hPRCP
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P42785 (PRCP) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T39 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 30459171, 25813380
N47 N-Glycosylation GlyGen 23090970, 29741879, 24190977
S49 O-Glycosylation GlyGen 34019948, 35289036
N63 N-Glycosylation GlyGen 24190977
K66 Ubiquitination PhosphoSitePlus
K77 Ubiquitination PhosphoSitePlus
N101 N-Glycosylation GlyGen   UniProt 20540760
K137 Ubiquitination PhosphoSitePlus
T164 Phosphorylation PhosphoSitePlus
N317 N-Glycosylation GlyGen   UniProt 20540760, 19159218
N336 N-Glycosylation GlyGen   UniProt 20540760
N345 N-Glycosylation GlyGen   UniProt 20540760
N415 N-Glycosylation GlyGen   UniProt 29741879, 20540760, 19159218
S418 O-Glycosylation GlyGen 34019948, 35289036
T420 O-Glycosylation GlyGen 34019948, 35289036
K462 Ubiquitination PhosphoSitePlus
S469 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K137 M137 Biomuta DOID:1324 / lung cancer [ cosmic ]
N345 H345 Biomuta DOID:363 / uterine cancer [ icgc ]
K462 T462 Biomuta DOID:10534 / stomach cancer [ cosmic ]
K462 R462 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
S469 F469 Biomuta DOID:4159 / skin cancer [ cosmic ]