iPTMnet Report for P42658 (DPP6)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P42658 / DPP6_HUMAN
Protein Name Dipeptidyl aminopeptidase-like protein 6
Gene Name Name: DPP6
Organism Homo sapiens (Human)

PRO ID PR:P42658
DAG View
PRO Name dipeptidyl aminopeptidase-like protein 6 (human)
Definition A dipeptidyl aminopeptidase-like protein 6 that is encoded in the genome of human.
Short Label hDPP6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P42658 (DPP6) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
R66 Methylation PhosphoSitePlus
R68 Methylation PhosphoSitePlus
N173 N-Glycosylation GlyGen   UniProt 15476821
S238 Phosphorylation PhosphoSitePlus
Y263 Phosphorylation PhosphoSitePlus
Y264 Phosphorylation PhosphoSitePlus
S277 Phosphorylation PhosphoSitePlus
T278 Phosphorylation PhosphoSitePlus
N319 N-Glycosylation GlyGen   UniProt 15476821
N404 N-Glycosylation GlyGen   UniProt 15476821
N535 N-Glycosylation GlyGen   UniProt 15476821
N566 N-Glycosylation GlyGen   UniProt 15476821
K671 Acetylation PhosphoSitePlus
K697 Acetylation PhosphoSitePlus
Y700 Phosphorylation PhosphoSitePlus
Y713 Phosphorylation PhosphoSitePlus
Y716 Phosphorylation PhosphoSitePlus
N813 N-Glycosylation GlyGen   UniProt 15476821
S815 O-Glycosylation GlyGen 29351928
T855 Phosphorylation PhosphoSitePlus
T857 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T278 S278 Biomuta DOID:1324 / lung cancer [ cosmic ]
N535 S535 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
Y716 * Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
T855 I855 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
T857 I857 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]