Protein Information

Cytoscape View


UniProt AC / UniProt ID P42568 / AF9_HUMAN
Protein Name Protein AF-9
Gene Name Name: MLLT3
Synonyms:AF9,YEATS3;
Organism Homo sapiens (Human)

PRO ID PR:P42568
DAG View
PRO Name protein AF-9 (human)
Definition A protein AF-9 that is encoded in the genome of human.
Short Label hMLLT3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P42568 (MLLT3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S58 Phosphorylation PhosphoSitePlus
S151 Phosphorylation PhosphoSitePlus
S152 Phosphorylation PhosphoSitePlus
S153 Phosphorylation PhosphoSitePlus
S154 Phosphorylation PhosphoSitePlus
S155 Phosphorylation PhosphoSitePlus
S160 Phosphorylation PhosphoSitePlus
S161 Phosphorylation PhosphoSitePlus
S162 Phosphorylation PhosphoSitePlus
S163 Phosphorylation PhosphoSitePlus
S165 Phosphorylation PhosphoSitePlus
S168 Phosphorylation PhosphoSitePlus
S169 Phosphorylation PhosphoSitePlus
S170 Phosphorylation PhosphoSitePlus
S171 Phosphorylation PhosphoSitePlus
S172 Phosphorylation PhosphoSitePlus
S177 Phosphorylation PhosphoSitePlus
S178 Phosphorylation PhosphoSitePlus
S179 Phosphorylation PhosphoSitePlus
S180 Phosphorylation PhosphoSitePlus
S181 Phosphorylation PhosphoSitePlus
S184 Phosphorylation PhosphoSitePlus
K235 Acetylation PhosphoSitePlus
K240 Acetylation PhosphoSitePlus
K254 Acetylation PhosphoSitePlus
K264 Sumoylation PhosphoSitePlus
S288 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S290 Phosphorylation PhosphoSitePlus
S294 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18691976, 18669648, 23186163
K300 Methylation PhosphoSitePlus
S301 Phosphorylation PhosphoSitePlus
S302 Phosphorylation PhosphoSitePlus
S303 Phosphorylation PhosphoSitePlus
K308 Methylation PhosphoSitePlus
S309 Phosphorylation PhosphoSitePlus
T319 Phosphorylation PhosphoSitePlus
S321 Phosphorylation PhosphoSitePlus
K330 Acetylation PhosphoSitePlus
S331 Phosphorylation PhosphoSitePlus
K334 Acetylation PhosphoSitePlus
K337 Acetylation PhosphoSitePlus
K339 Sumoylation PhosphoSitePlus
S364 Phosphorylation PhosphoSitePlus
S385 Phosphorylation PhosphoSitePlus
S386 Phosphorylation PhosphoSitePlus
S387 Phosphorylation PhosphoSitePlus
S388 Phosphorylation PhosphoSitePlus
S412 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332
S419 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 19690332
S429 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
S446 Phosphorylation O00141 (SGK1) neXtProt 17332896
T473 Phosphorylation PhosphoSitePlus
S483 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18691976, 18669648, 23186163, ...20068231
S488 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K557 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S288 Phosphorylation HPRD 18669648
S294 Phosphorylation HPRD 18691976, 18669648
S364 Phosphorylation HPRD 18452278
S412 Phosphorylation HPRD 18691976, 18669648, 18452278
S419 Phosphorylation HPRD 18691976, 18669648, 18452278
S429 Phosphorylation HPRD 18691976, 18669648, 18452278
S483 Phosphorylation HPRD 18691976, 18767875, 18452278, ...19651622, 18669648, 20068231
S488 Phosphorylation HPRD 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S161 N161 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ]
S163 R163 Biomuta DOID:9256 / colorectal cancer [ icgc ]
S169 I169 Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]
S172 I172 Biomuta DOID:363 / uterine cancer [ tcga ]
S180 R180 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]
S184 N184 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]
K240 E240 Biomuta DOID:3070 / malignant glioma [ cosmic, icgc, tcga ]
K264 R264 Biomuta DOID:363 / uterine cancer [ tcga ]
S288 L288 Biomuta DOID:1909 / melanoma [ tcga ]
K300 M300 Biomuta DOID:3571 / liver cancer [ icgc ]
K300 N300 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
S321 F321 Biomuta DOID:1324 / lung cancer [ tcga ] DOID:3070 / malignant glioma [ tcga ]
S331 Y331 Biomuta DOID:3571 / liver cancer [ icgc ]
K334 N334 Biomuta DOID:3070 / malignant glioma [ tcga ]
K339 N339 Biomuta DOID:363 / uterine cancer [ tcga ]
S388 C388 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc, tcga ]