iPTMnet Report for P42345 (MTOR)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P42345 / MTOR_HUMAN
Protein Name Serine/threonine-protein kinase mTOR
Gene Name Name: MTOR
Synonyms:FRAP,FRAP1,FRAP2,RAFT1,RAPT1;
Organism Homo sapiens (Human)

PRO ID PR:P42345
DAG View
PRO Name serine/threonine-protein kinase mTOR (human)
Definition A serine/threonine-protein kinase mTOR that is encoded in the genome of human.
Short Label hMTOR
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P42345 (MTOR) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378
K42 Ubiquitination PhosphoSitePlus
K84 Ubiquitination PhosphoSitePlus
S92 Phosphorylation PhosphoSitePlus
T102 Phosphorylation PhosphoSitePlus
Y110 Phosphorylation PhosphoSitePlus
K128 Ubiquitination PhosphoSitePlus
K230 Ubiquitination PhosphoSitePlus
K243 Ubiquitination PhosphoSitePlus
K251 Ubiquitination PhosphoSitePlus
K298 Ubiquitination PhosphoSitePlus
K301 Ubiquitination PhosphoSitePlus
T308 Phosphorylation PhosphoSitePlus   RLIMS-P 26880557, 26535060, 27076228, ...23989949, 24418989, 31922221
K309 Ubiquitination PhosphoSitePlus
T314 Phosphorylation PhosphoSitePlus
K369 Ubiquitination PhosphoSitePlus
K379 Ubiquitination PhosphoSitePlus
K384 Ubiquitination PhosphoSitePlus
K449 Ubiquitination PhosphoSitePlus
K533 Ubiquitination PhosphoSitePlus
S567 Phosphorylation HPRD   PhosphoSitePlus   RLIMS-P   UniProt 18691976, 27043084, 20068231, ...19369195
K616 Ubiquitination PhosphoSitePlus
T631 Phosphorylation PhosphoSitePlus
T665 Phosphorylation PhosphoSitePlus
S719 Phosphorylation PhosphoSitePlus
K777 Ubiquitination PhosphoSitePlus
Y861 Phosphorylation PhosphoSitePlus
T880 Phosphorylation PhosphoSitePlus
K898 Ubiquitination PhosphoSitePlus
K900 Ubiquitination PhosphoSitePlus
S909 Phosphorylation PhosphoSitePlus
S916 Phosphorylation PhosphoSitePlus
S918 Phosphorylation PhosphoSitePlus
S1131 Phosphorylation PhosphoSitePlus
K1133 Ubiquitination PhosphoSitePlus
T1162 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19651622, 18669648, 19691289, ...20068231
S1166 Phosphorylation HPRD   PhosphoSitePlus 17322306, 19651622, 20068231, ...18767875
S1171 Phosphorylation PhosphoSitePlus
T1172 Phosphorylation PhosphoSitePlus
K1187 Ubiquitination PhosphoSitePlus
Y1188 Phosphorylation PhosphoSitePlus
K1197 Ubiquitination PhosphoSitePlus
K1218 Acetylation PhosphoSitePlus   UniProt 19608861
K1218 Ubiquitination PhosphoSitePlus
Y1232 Phosphorylation PhosphoSitePlus
K1256 Acetylation PhosphoSitePlus
K1256 Ubiquitination PhosphoSitePlus
K1257 Ubiquitination PhosphoSitePlus
S1261 Phosphorylation HPRD   PhosphoSitePlus   RLIMS-P   UniProt 18691976, 23186163, 18767875, ...19487463, 19651622, 20166139, 32409632
T1262 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
K1267 Ubiquitination PhosphoSitePlus
S1288 Phosphorylation PhosphoSitePlus
K1293 Ubiquitination PhosphoSitePlus
S1297 Phosphorylation PhosphoSitePlus
S1299 Phosphorylation PhosphoSitePlus
K1395 Ubiquitination PhosphoSitePlus
K1400 Ubiquitination PhosphoSitePlus
K1406 Ubiquitination PhosphoSitePlus
S1415 Phosphorylation PhosphoSitePlus   RLIMS-P 24990947
S1415 Phosphorylation O15111 (CHUK) PhosphoSitePlus 24990947
S1418 Phosphorylation PhosphoSitePlus
K1465 Ubiquitination PhosphoSitePlus
K1471 Ubiquitination PhosphoSitePlus
K1500 Ubiquitination PhosphoSitePlus
T1502 Phosphorylation PhosphoSitePlus
K1511 Ubiquitination PhosphoSitePlus
K1566 Ubiquitination PhosphoSitePlus
K1635 Ubiquitination PhosphoSitePlus
K1655 Ubiquitination PhosphoSitePlus
K1662 Ubiquitination PhosphoSitePlus
K1745 Ubiquitination PhosphoSitePlus
Y1804 Phosphorylation PhosphoSitePlus
S1821 Phosphorylation PhosphoSitePlus
S1847 Phosphorylation HPRD 18691976
S1849 Phosphorylation HPRD 18691976
S1859 Phosphorylation PhosphoSitePlus
T1870 Phosphorylation PhosphoSitePlus
S1874 Phosphorylation PhosphoSitePlus
T1876 Phosphorylation PhosphoSitePlus
Y1880 Phosphorylation PhosphoSitePlus
S1893 Phosphorylation PhosphoSitePlus
T1948 Phosphorylation PhosphoSitePlus
K1993 Ubiquitination PhosphoSitePlus
K2045 Ubiquitination PhosphoSitePlus
K2066 Ubiquitination PhosphoSitePlus
S2069 Phosphorylation PhosphoSitePlus
S2155 Phosphorylation PhosphoSitePlus
S2159 Phosphorylation neXtProt   PhosphoSitePlus   RLIMS-P   UniProt 21576368, 31530866, 29150432
T2164 Phosphorylation neXtProt   PhosphoSitePlus   RLIMS-P   UniProt 21576368
K2166 Ubiquitination PhosphoSitePlus
T2173 Phosphorylation UniProt 24247430
K2218 Ubiquitination PhosphoSitePlus
K2301 Ubiquitination PhosphoSitePlus
K2370 Ubiquitination PhosphoSitePlus
T2380 Phosphorylation PhosphoSitePlus
T2434 Phosphorylation PhosphoSitePlus
T2436 Phosphorylation PhosphoSitePlus
S2442 Phosphorylation PhosphoSitePlus   RLIMS-P 35566660, 30461193
T2444 Phosphorylation HPRD   PhosphoSitePlus 18691976
T2446 Phosphorylation HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 15905173, 14970221, 25200751, ...33893278, 26384306, 17643959, 29719593, 26855590, 26418879, 10910062
T2446 Phosphorylation P23443 (RPS6KB1) neXtProt   PhosphoSitePlus   Signor 15905173
T2446 Phosphorylation P31749 (AKT1) HPRD   neXtProt   PhosphoSitePlus 14970221, 10910062
T2446 Phosphorylation Q13131 (PRKAA1) HPRD 14970221
T2446 Phosphorylation Q15418 (RPS6KA1) HPRD 15905173
S2448 Phosphorylation HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 24984001, 31195027, 25721419, ...17142137, 28857517, 21132000, 26775697, 31546610, 15625077, 33679734, 30036188, 33664437, 25153728, 17110594, 24416349, 19664994, 28102849, 21798089, 32642725, 31332166, 26158518, 25183163, 31388935, 23348097, 30813295, 25724269, 29448085, 30067827, 33806593, 27769069, 24303161, 31404320, 31160490, 25902785, 29662627, 26329846, 30282964, 23861877, 25624750, 18466352, 23471000, 26940018, 27654866, 27259258, 17976640, 26317515, 28591197, 20736160, 26496360, 30250025, 19834494, 30258945, 33523588, 24952732, 19125612, 32363163, 24496460, 30753671, 25028121, 26919097, 28481292, 33003310, 30633777, 21208419, 24932295, 17162089, 25356866, 29162840, 15899889, 29933163, 28400912, 24057571, 26580601, 25385184, 33849427, 33833996, 24384983, 26536660, 18691976, 23094058, 22039466, 31572212, 28652768, 22383503, 27486771, 32066788, 20152809, 11884412, 31601269, 30285764, 24810758, 28808322, 19019920, 25283550, 33226960, 30959969, 25978653, 24133625, 26879868, 19153210, 28750861, 21702994, 25592318, 28475412, 27506466, 30771309, 22421143, 30864709, 31037139, 28191279, 29712904, 25909895, 31284427, 28675026, 26557719, 29472733, 33912163, 26734992, 33101031, 19587783, 26369790, 32576196, 27551516, 28252104, 30619462, 27096957, 22567115, 20144629, 26985829, 27903908, 29167516, 30622543, 29774133, 25460505, 30359321, 29396411, 29434840, 22422828, 19576515, 30755581, 17646396, 27223432, 23569215, 25793983, 26313911, 19055754, 26367276, 27239959, 31083403, 28061443, 17721885, 29755672, 33456359, 31586300, 24098154, 23557706, 27031247, 31247000, 26934000, 16934436, 25738356, 28974016, 25051975, 30073169, 36471885, 30716115, 19293927, 29552187, 33473107, 32460884, 30473630, 23095638, 21501117, 31294029, 24073922, 24587596, 26791827, 19079619, 18033679, 33414447, 31046771, 26641458, 32676067, 22817638, 32766308, 29233971, 30654190, 25945839, 22347457, 26413815, 24245980, 23632629, 24287900, 26674543, 33549048, 30599894, 23185989, 15388509, 26151180, 28903328, 22028912, 27957793, 25884331, 30758811, 25035961, 19959541, 24201812, 22357971, 27611696, 33526785, 33893278, 33731670, 26447757, 27517315, 12937293, 33249469, 29692710, 26909611, 28860574, 30326670, 20216949, 25302072, 27935582, 33967735, 31710966, 33923895, 35912992, 19244117, 15208671, 21430254, 24527093, 24262949, 25596749, 29423932, 22452803, 33411714, 26397133, 30699367, 27863387, 18577697, 24606695, 29190940, 24590896, 16263769, 27379204, 27903966, 23691056, 33071789, 25221647, 33723215, 25200751, 25792811, 29072696, 32707827, 29476223, 27147579, 32051464, 29876006, 15388791, 28881606, 23272152, 28592812, 22230498, 28923059, 29396506, 15963500, 22460505, 24376606, 24275569, 30514289, 19943972, 31889970, 21289204, 30986276, 28962438, 27494886, 29749377, 27070592, 22253983, 19956876, 19540199, 32012648, 33219302, 30208604, 32563986, 21840189, 31032225, 29533017, 33920772, 36386326, 28963552, 25026292, 29716528, 25609923, 27322212, 23537100, 23027611, 31031856, 31197106, 33845796, 32019055, 33907223, 24995775, 20459645, 19644030, 28272965, 30341283, 29463831, 30965356, 19641606, 31383875, 30274346, 14560963, 23415012, 25926716, 28146421, 29472585, 23349989, 29731844, 27656263, 26698679, 18276949, 32765083, 33920031, 23724051, 20484036, 32444674, 16886599, 15905173, 25815363, 17971512, 28675785, 23563240, 27329724, 27658964, 22969779, 26114294, 33718332, 27304189, 18668345, 30816192, 29780826, 29379304, 26397365, 14970221, 30373220, 26657290, 19145465, 24273605, 24887419, 24180592, 19549760, 27048233, 26775708, 30154572, 26384306, 28152510, 24691032, 23383195, 16584539, 28569781, 25296981, 27680387, 33509041, 24023012, 27264178, 21763421, 16952420, 32753891, 10910062, 29484131, 25834399, 29175420, 25005758, 29665227, 29331082, 30132043, 31089421, 26887051, 32103999, 25088800, 17178807, 30816216, 32943998, 32575925, 22886792, 31383843, 27098617, 25775774, 19439614, 26416965, 25020061, 33658929, 35783523, 16920842, 31428575, 27467530, 30675291, 33116125, 26417067, 29156703, 26291325, 26071201, 15292249, 29719593, 10567225, 32958058, 25849580, 32863214, 21937645, 28710431, 30108651, 30761524, 27227776, 27009203, 16288304, 28837154, 26437614, 33609078
S2448 Phosphorylation P23443 (RPS6KB1) HPRD   neXtProt   PhosphoSitePlus 15905173, 10910062, 19664994, ...15899889, 18691976
S2448 Phosphorylation P31749 (AKT1) HPRD   neXtProt   PhosphoSitePlus   Signor 18691976, 19664994, 10910062, ...15208671, 10567225
S2448 Phosphorylation Q15418 (RPS6KA1) HPRD 18691976, 19664994, 10910062
Y2449 Phosphorylation PhosphoSitePlus
S2450 Phosphorylation PhosphoSitePlus
S2454 Phosphorylation HPRD   neXtProt   PhosphoSitePlus   RLIMS-P 20804212, 19664994
S2454 Phosphorylation P42345 (MTOR) neXtProt   PhosphoSitePlus 20804212
T2471 Phosphorylation PhosphoSitePlus
T2473 Phosphorylation PhosphoSitePlus 20804212
T2473 Phosphorylation P42345 (MTOR) PhosphoSitePlus 20804212
T2474 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 20804212, 18669648
T2474 Phosphorylation P42345 (MTOR) PhosphoSitePlus 20804212
S2478 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 20804212, 18669648
S2478 Phosphorylation P42345 (MTOR) PhosphoSitePlus 20804212
S2481 Phosphorylation HPRD   IntAct   neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 19934253, 17142137, 26174628, ...24133625, 25035961, 19959541, 29463831, 31546610, 28745319, 33526785, 30771309, 23415012, 27517315, 33664437, 23349989, 21460630, 22786721, 20804212, 29731844, 28675026, 29692710, 27070592, 30326670, 16322256, 31710966, 19956839, 35912992, 19244117, 26656173, 27329724, 28860574, 30619462, 29379304, 30108651, 16920842, 29507660, 25460505, 27379204, 27903966, 31856761, 26329846, 29212252, 25596749, 26855590, 23861877, 30986276, 10702316, 28916818, 28650797, 25792811, 23471000, 23569215, 26940018, 26313911, 27259258, 27486771, 25296981, 28591197, 25210801, 30839155, 19834494, 33456359, 27835591, 21763421, 16263769, 23383195, 23272152, 26416965, 26880557, 19285014, 29175420, 24376606, 20668162, 21045808, 15388509, 24813396, 30073169, 30588010, 26071201, 21576368, 21084642, 26124292, 27611696, 29483523, 24628795, 27043084, 23095638, 32575925, 18669648, 29611762, 19540199, 31383843, 24670043, 28400912, 28794469, 29396506, 30374127, 27494886, 25385184, 31586300, 33849427, 29719593, 22347457, 24245980, 21818401, 30373220, 27239959, 22898869, 32066788, 23185989, 29991711, 30131676, 19019920, 24995775, 31046771, 20022946, 24185040, 12935885, 23007634
S2481 Phosphorylation P42345 (MTOR) HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   Signor   UniProt 20022946, 10702316, 18669648, ...20804212
K2489 Ubiquitination PhosphoSitePlus
K2496 Ubiquitination PhosphoSitePlus


P42345 (MTOR) as PTM Enzyme



Substrate Site Score Source PMID
O00141 (SGK1) S422 PhosphoSitePlus   Signor 18570873, 18925875
O00418 (EEF2K) S72 PhosphoSitePlus 21659604
O00418 (EEF2K) S74 PhosphoSitePlus 21659604
O75179 (ANKRD17) S2045 PhosphoSitePlus 21659604
O75179 (ANKRD17) S2047 PhosphoSitePlus 21659604
O75385 (ULK1) S638 PhosphoSitePlus 21383122
O75385 (ULK1) S758 PhosphoSitePlus   Signor 21383122
O95747 (OXSR1) S339 PhosphoSitePlus 24191005
O95817 (BAG3) T285 PhosphoSitePlus 21659604
O95817 (BAG3) S289 PhosphoSitePlus 21659604
O96018 (APBA3) T5 PhosphoSitePlus 24164895
O96018 (APBA3) S7 PhosphoSitePlus 24164895
P03372 (ESR1) S104 PhosphoSitePlus 26522726
P03372 (ESR1) S106 PhosphoSitePlus 26522726
P04198 (MYCN) S62 PhosphoSitePlus 21659604
P19484 (TFEB) S122 RLIMS-P+ 28055300
P19484 (TFEB) S142 Signor 22343943
P19484 (TFEB) S211 Signor 22692423
P23443-2 (RPS6KB1) T389 PhosphoSitePlus 23928304
P23443-1 (RPS6KB1) T390 HPRD   phospho.ELM   Signor 11914378, 12370290, 11279232, ...18669648, 14560963, 20068231
P23443 (RPS6KB1) S394 HPRD   phospho.ELM   PhosphoSitePlus 9271440, 11914378, 12586835, ...18669648
P23443 (RPS6KB1) T412 HPRD   phospho.ELM   PhosphoSitePlus   Signor 20804212, 10579915, 17386266, ...12604610, 19346248, 12370290, 15809305, 15718470
P23443 (RPS6KB1) S434 phospho.ELM   PhosphoSitePlus 15809305
P23443 (RPS6KB1) S447 phospho.ELM 11914378
P26358 (DNMT1) S714 PhosphoSitePlus 21659604
P31749 (AKT1) T450 PhosphoSitePlus 21045808
P31749 (AKT1) S473 PhosphoSitePlus   Signor 22084251, 20804212, 21965657, ...23928304, 21157483, 20501647, 21592956, 15718470
P35568 (IRS1) S307 Signor 9335553
P40763 (STAT3) S727 Signor 18691976, 16740698
P42345 (MTOR) S2454 neXtProt   PhosphoSitePlus 20804212
P42345 (MTOR) T2473 PhosphoSitePlus 20804212
P42345 (MTOR) T2474 PhosphoSitePlus 20804212
P42345 (MTOR) S2478 PhosphoSitePlus 20804212
P42345 (MTOR) S2481 HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   Signor   UniProt 20022946, 10702316, 18669648, ...20804212
P51397 (DAP) S3 Signor 20537536
P51397 (DAP) S51 PhosphoSitePlus   Signor 20537536
P55199 (ELL) S309 PhosphoSitePlus 21659604
Q00613 (HSF1) S326 PhosphoSitePlus 22768106
Q13322 (GRB10) T155 PhosphoSitePlus 21659604
Q13322 (GRB10) S428 PhosphoSitePlus 21659604
Q13322 (GRB10) S476 PhosphoSitePlus 21659604
Q13541 (EIF4EBP1) T36 Signor 9465032, 17510057
Q13541 (EIF4EBP1) T37 HPRD   phospho.ELM   PhosphoSitePlus   Signor 11777913, 20804212, 19413330, ...17386266, 19346248, 10942774, 19664995, 9465032, 12370290, 20068231, 21659604, 20537536, 12747827, 18669648, 19651622
Q13541 (EIF4EBP1) T41 PhosphoSitePlus 21659604
Q13541 (EIF4EBP1) S44 PhosphoSitePlus 21659604
Q13541 (EIF4EBP1) T45 Signor 9465032, 17510057
Q13541 (EIF4EBP1) T46 HPRD   phospho.ELM   PhosphoSitePlus   Signor 11777913, 19413330, 9465032, ...20804212, 17386266, 19346248, 10942774, 18669648, 19664995, 19651622, 12370290, 20537536, 12747827, 20068231
Q13541 (EIF4EBP1) S65 HPRD   phospho.ELM   PhosphoSitePlus   Signor 11777913, 17287340, 18767875, ...10942774, 19664995, 19651622, 18669648, 12747827, 12912989, 20068231
Q13541 (EIF4EBP1) T70 HPRD   phospho.ELM   PhosphoSitePlus   Signor 17287340, 10942774, 19664995, ...12912989, 19651622, 12370290, 12747827, 18669648, 20068231
Q13541 (EIF4EBP1) S83 HPRD   phospho.ELM   Signor 10779345, 9204908, 18669648, ...9092573, 9405468
Q13541 (EIF4EBP1) S101 phospho.ELM 12912989
Q14693 (LPIN1) S106 neXtProt 21816276
Q14693 (LPIN1) S438 neXtProt 21816276
Q5T4S7 (UBR4) S2932 PhosphoSitePlus 21659604
Q641Q2 (WASHC2A) S700 PhosphoSitePlus 21659604
Q641Q2 (WASHC2A) S704 PhosphoSitePlus 21659604
Q6PKG0 (LARP1) S766 PhosphoSitePlus 21659604
Q6PKG0 (LARP1) S774 PhosphoSitePlus 21659604
Q86TB9 (PATL1) S179 PhosphoSitePlus 21659604
Q86TB9 (PATL1) S184 PhosphoSitePlus 21659604
Q8IYB3 (SRRM1) T572 PhosphoSitePlus 21659604
Q8IYB3 (SRRM1) T574 PhosphoSitePlus 21659604
Q8N122 (RPTOR) S855 Signor 19864431
Q8N122 (RPTOR) S859 PhosphoSitePlus   Signor 19346248, 19864431
Q8N122 (RPTOR) S863 PhosphoSitePlus   Signor 19346248, 19864431
Q8TB45 (DEPTOR) S265 PhosphoSitePlus 22017875
Q8TB45 (DEPTOR) S286 PhosphoSitePlus 22017875
Q8TB45 (DEPTOR) S293 PhosphoSitePlus   Signor 22017875, 22017877
Q8TB45 (DEPTOR) T295 PhosphoSitePlus 22017875
Q8TB45 (DEPTOR) S299 neXtProt   PhosphoSitePlus   Signor 22017875, 22017877
Q96B36 (AKT1S1) S183 PhosphoSitePlus   Signor 17517883, 18372248
Q96B36 (AKT1S1) S221 PhosphoSitePlus 18372248
Q96F24 (NRBF2) S113 Signor 28059666
Q96F24 (NRBF2) S120 Signor 28059666
Q9BPZ7 (MAPKAP1) S260 PhosphoSitePlus 23928304
Q9C0C7 (AMBRA1) S52 PhosphoSitePlus 23524951
Q9H063 (MAF1) S60 PhosphoSitePlus   Signor 20516213, 21659604
Q9H063 (MAF1) S68 PhosphoSitePlus   Signor 20516213, 20233713, 21659604
Q9H063 (MAF1) S75 PhosphoSitePlus   Signor 20543138, 20516213, 20233713
Q9H1K1 (ISCU) S14 PhosphoSitePlus   Signor 23508953
Q9H4A3 (WNK1) S2032 PhosphoSitePlus 21659604
Q9H5H4 (ZNF768) S139 PhosphoSitePlus 21659604
Q9H8M2 (BRD9) S588 PhosphoSitePlus 21659604
Q9NQG5 (RPRD1B) S166 PhosphoSitePlus 21659604
Q9P2Y5 (UVRAG) S550 PhosphoSitePlus 26139536
Q9P2Y5 (UVRAG) S571 PhosphoSitePlus 26139536
Q9UBS0-1 (RPS6KB2) T228 HPRD 11733037
Q9UBS0-1 (RPS6KB2) S370 HPRD 11733037
Q9UBS0 (RPS6KB2) T388 HPRD   phospho.ELM 14560963, 11733037
Q9UQ35 (SRRM2) S1318 PhosphoSitePlus 21659604
Q9UQ35 (SRRM2) S1326 PhosphoSitePlus 21659604
Q9UQ35 (SRRM2) S1329 PhosphoSitePlus 21659604
Q9Y2J4 (AMOTL2) S759 PhosphoSitePlus 25998128
Q9Y6W6 (DUSP10) S224 PhosphoSitePlus 25568665
Q9Y6W6 (DUSP10) S230 PhosphoSitePlus 25568665


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P42345 (MTOR) S2481 Q3U182 (Crtc2) unknown eFIP 24479521
Phosphorylation P42345 (MTOR) S2481 P42345 (MTOR) unknown eFIP 31586300
Phosphorylation Q6R327 (RICTOR) T1135 P42345 (MTOR) inhibited_association eFIP 27239959


Proteoform PPIs

Protein 1 Relation Protein 2 Source PMID
PR:P42345 (hMTOR) Interaction PR:000035446 (hTP53/iso:1/Phos:1) PRO 11602639


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K42 M42 Biomuta DOID:1324 / lung cancer [ cosmic ]
K42 N42 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S92 R92 Biomuta DOID:1324 / lung cancer [ cosmic ]
Y110 S110 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
K298 E298 Biomuta DOID:10283 / prostate cancer [ cosmic ]
T314 N314 Biomuta DOID:263 / kidney cancer [ cosmic ]
K384 N384 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
K384 R384 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
T880 A880 Biomuta DOID:4159 / skin cancer [ cosmic ]
S1166 R1166 Biomuta DOID:3571 / liver cancer [ cosmic ]
Y1188 H1188 Biomuta DOID:263 / kidney cancer [ cosmic ]
T1262 A1262 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1297 L1297 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S1415 F1415 Biomuta DOID:1319 / brain cancer [ icgc ]
S1415 C1415 Biomuta DOID:10283 / prostate cancer [ cosmic ]
K1465 N1465 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T1502 I1502 Biomuta DOID:10534 / stomach cancer [ cosmic ]
T1502 A1502 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
K1635 T1635 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K1655 N1655 Biomuta DOID:1964 / fallopian tube cancer [ cosmic ]
K1662 M1662 Biomuta DOID:263 / kidney cancer [ cosmic ]
T1948 M1948 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ]
S2155 F2155 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T2446 M2446 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S2448 F2448 Biomuta DOID:4159 / skin cancer [ cosmic ]
T2471 M2471 Biomuta DOID:10283 / prostate cancer [ cosmic ]