Protein Information

Cytoscape View


UniProt AC / UniProt ID P42336 / PK3CA_HUMAN
Protein Name Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
Gene Name Name: PIK3CA
Organism Homo sapiens (Human)

PRO ID PR:P42336
DAG View
PRO Name phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (human)
Definition A phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform that is encoded in the genome of human.
Short Label hPIK3CA
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P42336 (PIK3CA) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S6 Phosphorylation RLIMS-P 21362200
Y246 Phosphorylation PhosphoSitePlus
Y294 Phosphorylation PhosphoSitePlus
S306 Phosphorylation PhosphoSitePlus
S312 Phosphorylation PhosphoSitePlus
T313 Phosphorylation PhosphoSitePlus
T315 Phosphorylation PhosphoSitePlus
Y317 Phosphorylation PhosphoSitePlus
S332 Phosphorylation PhosphoSitePlus
Y355 Phosphorylation PhosphoSitePlus
Y361 Phosphorylation PhosphoSitePlus
S507 Phosphorylation PhosphoSitePlus
Y508 Phosphorylation PhosphoSitePlus
S509 Phosphorylation PhosphoSitePlus
Y584 Phosphorylation PhosphoSitePlus
Y698 Phosphorylation PhosphoSitePlus
S874 Phosphorylation PhosphoSitePlus
T876 Phosphorylation PhosphoSitePlus
T957 Phosphorylation PhosphoSitePlus
Y1038 Phosphorylation PhosphoSitePlus


P42336 (PIK3CA) as PTM Enzyme



Substrate Site Score Source PMID
P09493 (TPM1) S61 phospho.ELM   PhosphoSitePlus 16094730
P23443 (RPS6KB1) T252 PhosphoSitePlus 11684675
P23443-1 (RPS6KB1) T390 HPRD 18669648, 11279232, 20068231
P23443 (RPS6KB1) T412 PhosphoSitePlus 11684675
P27986 (PIK3R1) S608 neXtProt   phospho.ELM   PhosphoSitePlus 9446654, 23270540, 14729945
P32927 (CSF2RB) S585 neXtProt 23526884