Protein Information

Cytoscape View


UniProt AC / UniProt ID P42331 / RHG25_HUMAN
Protein Name Rho GTPase-activating protein 25
Gene Name Name: ARHGAP25
Synonyms:KIAA0053;
Organism Homo sapiens (Human)

PRO ID PR:P42331
DAG View
PRO Name Rho GTPase-activating protein 25 (human)
Definition A Rho GTPase-activating protein 25 that is encoded in the genome of human.
Short Label hARHGAP25
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P42331 (ARHGAP25) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K4 Ubiquitination PhosphoSitePlus
K19 Ubiquitination PhosphoSitePlus
S25 Phosphorylation PhosphoSitePlus
K208 Ubiquitination PhosphoSitePlus
T226 Phosphorylation PhosphoSitePlus
S233 Phosphorylation PhosphoSitePlus
S362 Phosphorylation PhosphoSitePlus   UniProt 23186163
S379 Phosphorylation PhosphoSitePlus
S391 Phosphorylation PhosphoSitePlus
T393 Phosphorylation PhosphoSitePlus
S395 Phosphorylation PhosphoSitePlus   UniProt 19690332
S397 Phosphorylation PhosphoSitePlus
S398 Phosphorylation PhosphoSitePlus
T400 Phosphorylation PhosphoSitePlus
S401 Phosphorylation PhosphoSitePlus
S436 Phosphorylation PhosphoSitePlus
T442 Phosphorylation PhosphoSitePlus
K461 Acetylation PhosphoSitePlus
S471 Phosphorylation PhosphoSitePlus
T485 Phosphorylation PhosphoSitePlus
S487 Phosphorylation PhosphoSitePlus
S494 Phosphorylation PhosphoSitePlus
T499 Phosphorylation PhosphoSitePlus
S507 Phosphorylation PhosphoSitePlus
S511 Phosphorylation PhosphoSitePlus
S517 Phosphorylation PhosphoSitePlus
S520 Phosphorylation PhosphoSitePlus
S533 Phosphorylation PhosphoSitePlus
S545 Phosphorylation PhosphoSitePlus
Y571 Phosphorylation PhosphoSitePlus
Y583 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S363 Phosphorylation HPRD 20058876


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K208 N208 Biomuta DOID:3571 / liver cancer [ icgc ]
S233 A233 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
T485 M485 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
S487 Y487 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
S494 C494 Biomuta DOID:1324 / lung cancer [ cosmic ]