iPTMnet Report for P42261 (GRIA1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P42261 / GRIA1_HUMAN
Protein Name Glutamate receptor 1 precursor
Gene Name Name: GRIA1
Synonyms:GLUH1,GLUR1;
Organism Homo sapiens (Human)

PRO ID PR:P42261
DAG View
PRO Name glutamate receptor 1 (human)
Definition A glutamate receptor 1 that is encoded in the genome of human.
Short Label hGRIA1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P42261 (GRIA1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y226 Phosphorylation PhosphoSitePlus
Y228 Phosphorylation PhosphoSitePlus
K265 Acetylation PhosphoSitePlus
Y294 Phosphorylation PhosphoSitePlus
T350 Phosphorylation PhosphoSitePlus
T362 O-Glycosylation GlyGen 30459171
T393 Phosphorylation PhosphoSitePlus
S511 Phosphorylation PhosphoSitePlus
S567 Phosphorylation Q9UQM7 (CAMK2A) PhosphoSitePlus   RLIMS-P 21135237
S754 Phosphorylation PhosphoSitePlus
S832 Phosphorylation P17252 (PRKCA) , Q9UQM7 (CAMK2A) neXtProt   PhosphoSitePlus   Signor 21610080, 22427672, 8663994
S834 Phosphorylation P17252 (PRKCA) phospho.ELM   PhosphoSitePlus 19503082
S836 Phosphorylation P17252 (PRKCA) phospho.ELM   PhosphoSitePlus 19503082
S849 O-Glycosylation GlyGen 28657654
S849 Phosphorylation P17252 (PRKCA) phospho.ELM   PhosphoSitePlus 12392933, 9407043, 18305116, ...12609872, 14973229, 8663994, 20089902
T858 Phosphorylation PhosphoSitePlus
S863 Phosphorylation P17612 (PRKACA) , Q13237 (PRKG2) neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor 26460013, 18305116, 8663994, ...18031684, 16330149
S880 Phosphorylation RLIMS-P 29247190
K885 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T393 Phosphorylation HPRD 18452278
S645 Phosphorylation Q13555 (CAMK2G) HPRD 7877986
S849 Phosphorylation Q13555 (CAMK2G) , P17252 (PRKCA) HPRD 9407043, 12609872, 8663994
S863 Phosphorylation P17612 (PRKACA) HPRD 8663994


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y294 C294 Biomuta DOID:5041 / esophageal cancer [ cosmic ]
T362 I362 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S511 C511 Biomuta DOID:1324 / lung cancer [ cosmic ]
S645 F645 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S832 F832 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
S834 G834 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S863 N863 Biomuta DOID:1612 / breast cancer [ cosmic ]