Protein Information

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UniProt AC / UniProt ID P42167 / LAP2B_HUMAN
Protein Name Lamina-associated polypeptide 2, isoforms beta/gamma
Gene Name Name: TMPO
Synonyms:LAP2;
Organism Homo sapiens (Human)

PRO ID PR:P42167
DAG View
PRO Name lamina-associated polypeptide 2 isoforms beta/gamma/zeta (human)
Definition A lamina-associated polypeptide 2 (human), isoforms beta, gamma, and zeta.
Short Label hTMPO/iso:[beta/gamma/zeta]
Category organism-seqgroup

Interactive Sequence View

Select/align proteoforms across species


P42167 (TMPO) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S9 Phosphorylation PhosphoSitePlus
T12 Phosphorylation PhosphoSitePlus
K13 Sumoylation PhosphoSitePlus
K17 Sumoylation PhosphoSitePlus
S18 Phosphorylation PhosphoSitePlus
T26 Phosphorylation PhosphoSitePlus
R50 Methylation PhosphoSitePlus
T57 Phosphorylation PhosphoSitePlus   UniProt 18669648
S59 Phosphorylation PhosphoSitePlus   UniProt 21406692
K60 Acetylation PhosphoSitePlus
K60 Ubiquitination PhosphoSitePlus
S66 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 16083285, 23186163, 17081983, ...15302935, 18669648, 24275569, 19690332
S67 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 16083285, 23186163, 17081983, ...15302935, 18669648, 24275569, 19690332
T74 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18691976, 21406692, 23186163, ...17081983, 18220336, 15302935, 18669648, 24275569, 19690332, 20068231
S79 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19690332, ...17081983
R86 Methylation PhosphoSitePlus
S87 Phosphorylation PhosphoSitePlus
T96 Phosphorylation PhosphoSitePlus
T99 Phosphorylation PhosphoSitePlus
K107 Ubiquitination PhosphoSitePlus
T113 Phosphorylation PhosphoSitePlus
T116 Phosphorylation PhosphoSitePlus
K126 Ubiquitination PhosphoSitePlus
Y127 Phosphorylation PhosphoSitePlus
T137 Phosphorylation PhosphoSitePlus
T154 Phosphorylation PhosphoSitePlus   UniProt 19690332
S156 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 20068231
S158 Phosphorylation PhosphoSitePlus
S159 Phosphorylation PhosphoSitePlus
T160 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 18669648, ...24275569, 19690332, 20068231
T164 Phosphorylation PhosphoSitePlus   UniProt 18669648, 23186163
S166 Phosphorylation PhosphoSitePlus
S167 Phosphorylation phospho.ELM   PhosphoSitePlus 15302935
S168 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 15302935, 23186163
T172 Phosphorylation PhosphoSitePlus
S177 Phosphorylation PhosphoSitePlus   UniProt 18669648
S180 Phosphorylation PhosphoSitePlus   UniProt 18669648, 23186163
Y183 Phosphorylation PhosphoSitePlus
S184 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983
S190 Phosphorylation PhosphoSitePlus   UniProt 23186163
K207 Acetylation PhosphoSitePlus
K207 Methylation PhosphoSitePlus
T208 Phosphorylation PhosphoSitePlus
T211 Phosphorylation PhosphoSitePlus   UniProt 20068231
K213 Ubiquitination PhosphoSitePlus
S222 Phosphorylation PhosphoSitePlus   UniProt 23186163
Y223 Phosphorylation PhosphoSitePlus
S224 Phosphorylation PhosphoSitePlus   UniProt 23186163
S235 Phosphorylation PhosphoSitePlus
T247 Phosphorylation PhosphoSitePlus
S250 Phosphorylation PhosphoSitePlus   UniProt 23186163
T251 Phosphorylation PhosphoSitePlus
S254 Phosphorylation PhosphoSitePlus   UniProt 23186163
T257 Phosphorylation PhosphoSitePlus
T264 Phosphorylation PhosphoSitePlus
S265 Phosphorylation PhosphoSitePlus   UniProt 23186163, 20068231
S276 Phosphorylation PhosphoSitePlus
T279 Phosphorylation PhosphoSitePlus
T284 Phosphorylation PhosphoSitePlus
S288 Phosphorylation PhosphoSitePlus
S289 Phosphorylation PhosphoSitePlus
S292 Phosphorylation PhosphoSitePlus   UniProt 19690332
T299 Phosphorylation PhosphoSitePlus
K303 Methylation PhosphoSitePlus
K303 Ubiquitination PhosphoSitePlus
S306 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18691976, 23186163, 17081983, ...18220336, 18669648, 24275569, 17693683, 19690332, 20068231, 17924679
T312 Phosphorylation PhosphoSitePlus   UniProt 20068231
S315 Phosphorylation PhosphoSitePlus   UniProt 18669648, 23186163, 20068231, ...18220336
K323 Ubiquitination PhosphoSitePlus
K324 Ubiquitination PhosphoSitePlus
K334 Acetylation PhosphoSitePlus
K334 Ubiquitination PhosphoSitePlus
T335 Phosphorylation PhosphoSitePlus
K346 Ubiquitination PhosphoSitePlus
Y351 Phosphorylation PhosphoSitePlus
S354 Phosphorylation PhosphoSitePlus
T355 Phosphorylation PhosphoSitePlus
T357 Phosphorylation PhosphoSitePlus
S360 Phosphorylation PhosphoSitePlus
S362 Phosphorylation PhosphoSitePlus   UniProt 18669648
K368 Ubiquitination PhosphoSitePlus
S378 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983
S385 Phosphorylation PhosphoSitePlus   UniProt 18669648, 23186163
S387 Phosphorylation PhosphoSitePlus
S388 Phosphorylation PhosphoSitePlus
K389 Ubiquitination PhosphoSitePlus
Y390 Phosphorylation PhosphoSitePlus
K393 Ubiquitination PhosphoSitePlus
Y394 Phosphorylation PhosphoSitePlus
K401 Ubiquitination PhosphoSitePlus
S402 Phosphorylation PhosphoSitePlus   UniProt 23186163
K404 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S9 Phosphorylation HPRD 20068231
T12 Phosphorylation HPRD 20068231
T57 Phosphorylation HPRD 18669648
S59 Phosphorylation HPRD 19651622, 20068231
S66 Phosphorylation HPRD 19413330, 18691976, 16083285, ...17287340, 20230923, 19664994, 20058876, 18452278, 19651622, 18669648, 18707149, 20166139, 19415658, 20068231
S67 Phosphorylation HPRD 19413330, 18691976, 17287340, ...17081983, 20230923, 19664994, 20058876, 18452278, 19651622, 18669648, 18707149, 20166139, 19415658, 20068231
T74 Phosphorylation HPRD 19413330, 18691976, 20230923, ...20058876, 19664994, 18452278, 17322306, 18669648, 19651622, 20166139, 19415658, 20068231
S79 Phosphorylation HPRD 18669648, 17287340, 17081983
S87 Phosphorylation HPRD 17287340
T96 Phosphorylation HPRD 17287340
T99 Phosphorylation HPRD 17287340
T137 Phosphorylation HPRD 17287340, 20068231
T154 Phosphorylation HPRD 18669648, 17081983, 20068231
S156 Phosphorylation HPRD 19651622, 18669648, 17081983, ...20068231, 18212344
S158 Phosphorylation HPRD 18691976, 18491316, 19664995, ...18452278, 17322306, 18669648, 20166139, 20068231
S159 Phosphorylation HPRD 19413330, 18491316, 17287340, ...17081983, 19664995, 18452278, 18669648, 20068231
T160 Phosphorylation HPRD 19413330, 18491316, 17287340, ...18767875, 20058876, 19691289, 19664995, 17322306, 18669648, 18452278, 19415658, 20068231, 17924679
T164 Phosphorylation HPRD 20166139, 18669648, 17081983, ...20068231
S166 Phosphorylation HPRD 20166139, 18669648, 20068231
S167 Phosphorylation HPRD 18669648
S168 Phosphorylation HPRD 19651622, 18669648, 19691289
T172 Phosphorylation HPRD 18669648
S177 Phosphorylation HPRD 19651622, 18669648, 20068231, ...18452278
S180 Phosphorylation HPRD 18669648, 17081983, 20068231, ...18452278
Y183 Phosphorylation HPRD 19651622, 18669648, 17081983, ...20068231, 18452278
S184 Phosphorylation HPRD 19651622, 18669648, 17081983, ...20068231, 18452278
T208 Phosphorylation HPRD 18669648, 18212344, 20068231, ...17924679
T211 Phosphorylation HPRD 18669648, 20068231
Y223 Phosphorylation HPRD 18669648
S235 Phosphorylation HPRD 20068231
T247 Phosphorylation HPRD 20068231
S265 Phosphorylation HPRD 20068231
T279 Phosphorylation HPRD 18669648
S306 Phosphorylation HPRD 18691976, 17081983, 19651622, ...18669648, 17693683, 17924679, 20068231, 20068230
T312 Phosphorylation HPRD 20068231
S315 Phosphorylation HPRD 18669648, 20068231
S354 Phosphorylation HPRD 18669648, 20068231
T355 Phosphorylation HPRD 18669648, 19415658, 20068231
T357 Phosphorylation HPRD 18669648
S360 Phosphorylation HPRD 18669648
S362 Phosphorylation HPRD 18669648, 20068231
S378 Phosphorylation HPRD 18669648, 19664994, 17081983, ...20068231, 17924679
S385 Phosphorylation HPRD 18669648, 20068231
S387 Phosphorylation HPRD 18669648
S388 Phosphorylation HPRD 18669648
Site PTM Type PTM Enzyme Score Source PMID
S9 Phosphorylation HPRD 20068231
T12 Phosphorylation HPRD 20068231
T57 Phosphorylation HPRD 18669648
S59 Phosphorylation HPRD 19651622, 20068231
S66 Phosphorylation HPRD 19413330, 18691976, 16083285, ...17287340, 20230923, 19664994, 20058876, 18452278, 19651622, 18669648, 18707149, 20166139, 19415658, 20068231
S67 Phosphorylation HPRD 19413330, 18691976, 17287340, ...17081983, 20230923, 19664994, 20058876, 18452278, 19651622, 18669648, 18707149, 20166139, 19415658, 20068231
T74 Phosphorylation HPRD 19413330, 18691976, 20230923, ...20058876, 19664994, 18452278, 17322306, 18669648, 19651622, 20166139, 19415658, 20068231
S79 Phosphorylation HPRD 18669648, 17287340, 17081983
S87 Phosphorylation HPRD 17287340
T96 Phosphorylation HPRD 17287340
T99 Phosphorylation HPRD 17287340
T137 Phosphorylation HPRD 17287340, 20068231
T154 Phosphorylation HPRD 18669648, 17081983, 20068231
S156 Phosphorylation HPRD 19651622, 18669648, 17081983, ...20068231, 18212344
S158 Phosphorylation HPRD 18691976, 18491316, 19664995, ...18452278, 17322306, 18669648, 20166139, 20068231
S159 Phosphorylation HPRD 19413330, 18491316, 17287340, ...17081983, 19664995, 18452278, 18669648, 20068231
T160 Phosphorylation HPRD 19413330, 18491316, 17287340, ...18767875, 20058876, 19691289, 19664995, 17322306, 18669648, 18452278, 19415658, 20068231, 17924679
T164 Phosphorylation HPRD 20166139, 18669648, 17081983, ...20068231
S166 Phosphorylation HPRD 20166139, 18669648, 20068231
S167 Phosphorylation HPRD 18669648
S168 Phosphorylation HPRD 19651622, 18669648, 19691289
T172 Phosphorylation HPRD 18669648
S177 Phosphorylation HPRD 19651622, 18669648, 20068231, ...18452278
S180 Phosphorylation HPRD 18669648, 17081983, 20068231, ...18452278
Y183 Phosphorylation HPRD 19651622, 18669648, 17081983, ...20068231, 18452278
S184 Phosphorylation HPRD 19651622, 18669648, 17081983, ...20068231, 18452278
T208 Phosphorylation HPRD   PhosphoSitePlus 18669648, 18212344, 20068231, ...17924679
T211 Phosphorylation HPRD 18669648, 20068231
K225 Ubiquitination PhosphoSitePlus
T226 Phosphorylation PhosphoSitePlus
S245 Phosphorylation HPRD 18669648, 20068231
T246 Phosphorylation HPRD 18669648, 19415658, 20068231
T248 Phosphorylation HPRD 18669648
S251 Phosphorylation HPRD 18669648
S253 Phosphorylation HPRD 18669648, 20068231
S269 Phosphorylation HPRD 18669648, 19664994, 17081983, ...20068231, 17924679
S276 Phosphorylation HPRD 18669648, 20068231
S278 Phosphorylation HPRD 18669648
S279 Phosphorylation HPRD 18669648