iPTMnet Report for P41567 (EIF1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P41567 / EIF1_HUMAN
Protein Name Eukaryotic translation initiation factor 1
Gene Name Name: EIF1
Synonyms:SUI1;
Organism Homo sapiens (Human)

PRO ID PR:P41567
DAG View
PRO Name eukaryotic translation initiation factor 1 (human)
Definition A eukaryotic translation initiation factor 1 that is encoded in the genome of human.
Short Label hEIF1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P41567 (EIF1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 19413330, 21406692, 20068231
S2 Phosphorylation HPRD   PhosphoSitePlus   UniProt 23186163, 20068231
S9 Phosphorylation PhosphoSitePlus   UniProt 21406692, 23186163
K18 Ubiquitination PhosphoSitePlus
T27 Phosphorylation PhosphoSitePlus
Y30 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 15592455
K42 Ubiquitination PhosphoSitePlus
T43 Phosphorylation PhosphoSitePlus
T45 Phosphorylation HPRD 20068231
Y54 Phosphorylation HPRD 20068231
K56 Methylation PhosphoSitePlus
K58 Acetylation PhosphoSitePlus
K61 Acetylation PhosphoSitePlus
K66 Ubiquitination PhosphoSitePlus
C69 S-Nitrosylation dbSNO 22178444, 19366988, 18335467
T72 Phosphorylation PhosphoSitePlus
Y79 Phosphorylation PhosphoSitePlus
K91 Ubiquitination PhosphoSitePlus
C94 Methylation IEDB 31844290
K109 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S9 C9 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
K18 N18 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K56 E56 Biomuta DOID:3571 / liver cancer [ cosmic ]
K61 T61 Biomuta DOID:2531 / hematologic cancer [ cosmic ]