Protein Information

Cytoscape View


UniProt AC / UniProt ID P41252 / SYIC_HUMAN
Protein Name Isoleucine--tRNA ligase, cytoplasmic
Gene Name Name: IARS1
Synonyms:IARS;
Organism Homo sapiens (Human)

PRO ID PR:P41252
DAG View
PRO Name isoleucine--tRNA ligase, cytoplasmic (human)
Definition An isoleucine--tRNA ligase, cytoplasmic that is encoded in the genome of human.
Short Label hIARS1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P41252 (IARS1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 19413330
R81 Methylation PhosphoSitePlus
R82 Methylation PhosphoSitePlus
K98 Ubiquitination PhosphoSitePlus
K110 Ubiquitination PhosphoSitePlus
C120 S-Nitrosylation dbSNO 26338901
K132 Ubiquitination PhosphoSitePlus
Y167 Phosphorylation PhosphoSitePlus
Y173 Phosphorylation PhosphoSitePlus
K177 Acetylation PhosphoSitePlus
S264 Phosphorylation HPRD   PhosphoSitePlus 20068231
K268 Ubiquitination PhosphoSitePlus
S271 Phosphorylation PhosphoSitePlus
Y273 Phosphorylation PhosphoSitePlus
K285 Ubiquitination PhosphoSitePlus
K288 Acetylation PhosphoSitePlus
Y295 Phosphorylation PhosphoSitePlus
Y333 Phosphorylation PhosphoSitePlus
K344 Ubiquitination PhosphoSitePlus
S346 Phosphorylation PhosphoSitePlus
K371 Ubiquitination PhosphoSitePlus
K375 Ubiquitination PhosphoSitePlus
T405 Phosphorylation PhosphoSitePlus
K410 Ubiquitination PhosphoSitePlus
S414 Phosphorylation PhosphoSitePlus
Y434 Phosphorylation PhosphoSitePlus
K450 Methylation PhosphoSitePlus
K450 Ubiquitination PhosphoSitePlus
S516 Phosphorylation PhosphoSitePlus
K606 Ubiquitination PhosphoSitePlus
K617 Acetylation PhosphoSitePlus
K617 Ubiquitination PhosphoSitePlus
S630 Phosphorylation PhosphoSitePlus
K641 Ubiquitination PhosphoSitePlus
K672 Ubiquitination PhosphoSitePlus
Y680 Phosphorylation PhosphoSitePlus
S688 Phosphorylation HPRD   PhosphoSitePlus 20068231
T692 Phosphorylation HPRD   PhosphoSitePlus 20068231
T718 Phosphorylation PhosphoSitePlus
T773 Phosphorylation PhosphoSitePlus
T777 Phosphorylation PhosphoSitePlus
T798 Phosphorylation PhosphoSitePlus
S800 Phosphorylation PhosphoSitePlus
Y803 Phosphorylation PhosphoSitePlus
K816 Ubiquitination PhosphoSitePlus
K817 Ubiquitination PhosphoSitePlus
S823 Phosphorylation PhosphoSitePlus
S827 Phosphorylation PhosphoSitePlus
T840 Phosphorylation PhosphoSitePlus
K844 Acetylation PhosphoSitePlus
K844 Ubiquitination PhosphoSitePlus
Y845 Phosphorylation PhosphoSitePlus
K848 Ubiquitination PhosphoSitePlus
K861 Ubiquitination PhosphoSitePlus
K864 Ubiquitination PhosphoSitePlus
S865 Phosphorylation PhosphoSitePlus
K868 Ubiquitination PhosphoSitePlus
K878 Ubiquitination PhosphoSitePlus
K885 Ubiquitination PhosphoSitePlus
Y888 Phosphorylation PhosphoSitePlus
K903 Ubiquitination PhosphoSitePlus
K910 Ubiquitination PhosphoSitePlus
K917 Ubiquitination PhosphoSitePlus
S920 Phosphorylation PhosphoSitePlus
S921 Phosphorylation PhosphoSitePlus
K929 Ubiquitination PhosphoSitePlus
K1000 Ubiquitination PhosphoSitePlus
T1006 Phosphorylation PhosphoSitePlus
T1010 Phosphorylation PhosphoSitePlus
Y1012 Phosphorylation PhosphoSitePlus
K1014 Methylation PhosphoSitePlus
K1042 Acetylation PhosphoSitePlus
K1042 Ubiquitination PhosphoSitePlus
Y1044 Phosphorylation PhosphoSitePlus
S1047 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19413330, 21406692, 23186163, ...18767875, 19651622, 18669648, 19415658, 20068231, 17924679
S1049 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19651622, 18669648, 19415658, ...20068231
K1051 Acetylation PhosphoSitePlus
K1051 Ubiquitination PhosphoSitePlus
K1057 Ubiquitination PhosphoSitePlus
T1058 Phosphorylation PhosphoSitePlus   UniProt 23186163
K1061 Ubiquitination PhosphoSitePlus
K1113 Ubiquitination PhosphoSitePlus
K1115 Ubiquitination PhosphoSitePlus
S1116 Phosphorylation PhosphoSitePlus
S1120 Phosphorylation PhosphoSitePlus
S1146 Phosphorylation PhosphoSitePlus
S1148 Phosphorylation PhosphoSitePlus
T1234 Phosphorylation PhosphoSitePlus
T1238 Phosphorylation PhosphoSitePlus
K1244 Ubiquitination PhosphoSitePlus
K1249 Ubiquitination PhosphoSitePlus
T1250 Phosphorylation PhosphoSitePlus
Y1252 Phosphorylation PhosphoSitePlus