iPTMnet Report for P41222 (PTGDS)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P41222 / PTGDS_HUMAN
Protein Name Prostaglandin-H2 D-isomerase precursor
Gene Name Name: PTGDS
Synonyms:PDS;
Organism Homo sapiens (Human)

PRO ID PR:P41222
DAG View
PRO Name prostaglandin-H2 D-isomerase (human)
Definition A prostaglandin-H2 D-isomerase that is encoded in the genome of human.
Short Label hPTGDS
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P41222 (PTGDS) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S29 O-Glycosylation GlyGen   UniProt 23234360
N51 N-Glycosylation GlyGen   UniProt 8336134, 30237853, 19159218, ...24190977, 23090970, 20954982, 17259069, 29391424, 7525874, 19838169
S67 O-Glycosylation GlyGen 30237853
T73 O-Glycosylation GlyGen 30237853
N78 N-Glycosylation GlyGen   UniProt 16335952, 8336134, 30237853, ...23090970, 20954982, 26791533, 22171320, 7525874, 19139490, 19838169, 29391424, 29741879
T80 O-Glycosylation GlyGen 30237853
S81 O-Glycosylation GlyGen 28657654
N87 N-Glycosylation GlyGen 29391424
S106 Phosphorylation RLIMS-P 17259069
Y107 Phosphorylation PhosphoSitePlus
T147 Phosphorylation PhosphoSitePlus
Y149 Phosphorylation PhosphoSitePlus
S150 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
N51 N-Glycosylation PRO 7525874
N78 N-Glycosylation PRO 19838169, 26791533, 22171320, ...7525874


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T73 S73 Biomuta DOID:2394 / ovarian cancer [ icgc ]
N87 S87 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]