iPTMnet Report for P41221 (WNT5A)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P41221 / WNT5A_HUMAN
Protein Name Protein Wnt-5a precursor
Gene Name Name: WNT5A
Organism Homo sapiens (Human)

PRO ID PR:P41221
DAG View
PRO Name protein Wnt-5a (human)
Definition A protein Wnt-5a that is encoded in the genome of human.
Short Label hWNT5A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P41221 (WNT5A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
Y86 Phosphorylation PhosphoSitePlus
Y92 Phosphorylation PhosphoSitePlus
T99 Phosphorylation PhosphoSitePlus
N114 N-Glycosylation GlyGen 23090970, 29741879, 17117926, ...24190977
S116 Phosphorylation PhosphoSitePlus
T117 Phosphorylation PhosphoSitePlus
N120 N-Glycosylation GlyGen 17117926, 24190977
T121 Phosphorylation PhosphoSitePlus
S122 Phosphorylation PhosphoSitePlus
K194 Ubiquitination PhosphoSitePlus
K208 Ubiquitination PhosphoSitePlus
K261 Ubiquitination PhosphoSitePlus
Y270 Phosphorylation PhosphoSitePlus
S272 Phosphorylation PhosphoSitePlus
S280 Phosphorylation PhosphoSitePlus
K283 Ubiquitination PhosphoSitePlus
K348 Ubiquitination PhosphoSitePlus
C379 Methylation IEDB 31844290


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
Y86 D86 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T99 S99 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S116 N116 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S122 Y122 Biomuta DOID:9256 / colorectal cancer [ icgc ]
K261 E261 Biomuta DOID:3571 / liver cancer [ cosmic ]
Y270 * Biomuta DOID:363 / uterine cancer [ cosmic ]
K283 R283 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]