iPTMnet Report for P41220 (RGS2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P41220 / RGS2_HUMAN
Protein Name Regulator of G-protein signaling 2
Gene Name Name: RGS2
Synonyms:G0S8;ORFNames:GIG31;
Organism Homo sapiens (Human)

PRO ID PR:P41220
DAG View
PRO Name regulator of G-protein signaling 2 (human)
Definition A regulator of G-protein signaling 2 that is encoded in the genome of human.
Short Label hRGS2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P41220 (RGS2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S3 Phosphorylation PhosphoSitePlus
K39 Ubiquitination PhosphoSitePlus
S46 Phosphorylation Q13976 (PRKG1) neXtProt   phospho.ELM   PhosphoSitePlus 14608379
T54 Phosphorylation PhosphoSitePlus
K57 Ubiquitination PhosphoSitePlus
S64 Phosphorylation Q13976 (PRKG1) neXtProt   phospho.ELM   PhosphoSitePlus 14608379
K71 Ubiquitination PhosphoSitePlus
K121 Acetylation PhosphoSitePlus
K123 Acetylation PhosphoSitePlus
K127 Ubiquitination PhosphoSitePlus
K134 Ubiquitination PhosphoSitePlus
K142 Ubiquitination PhosphoSitePlus
K146 Ubiquitination PhosphoSitePlus
C169 Methylation IEDB 31844290
K175 Ubiquitination PhosphoSitePlus
Y178 Phosphorylation PhosphoSitePlus
S179 Phosphorylation PhosphoSitePlus
K201 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S46 Phosphorylation Q13976 (PRKG1) HPRD 14608379
S64 Phosphorylation Q13976 (PRKG1) HPRD 14608379


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S46 R46 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
K134 T134 Biomuta DOID:363 / uterine cancer [ icgc ]