iPTMnet Report for P41212 (ETV6)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P41212 / ETV6_HUMAN
Protein Name Transcription factor ETV6
Gene Name Name: ETV6
Synonyms:TEL,TEL1;
Organism Homo sapiens (Human)

PRO ID PR:P41212
DAG View
PRO Name transcription factor ETV6 (human)
Definition A transcription factor ETV6 that is encoded in the genome of human.
Short Label hETV6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P41212 (ETV6) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation PhosphoSitePlus
T4 Phosphorylation PhosphoSitePlus
K11 Acetylation PhosphoSitePlus   UniProt 19608861
K11 Sumoylation PhosphoSitePlus
S16 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 17081983
Y17 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648, 17081983
T18 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 17081983, 19651622, 18669648, ...19690332, 20068231
S22 Phosphorylation Q16539 (MAPK14) HPRD   phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 21406692, 17081983, 12435397, ...19651622, 18669648, 19690332, 20068231
S26 Phosphorylation PhosphoSitePlus
Y27 Phosphorylation PhosphoSitePlus
S29 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
S30 Phosphorylation PhosphoSitePlus
T31 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
S47 Phosphorylation PhosphoSitePlus
Y60 Phosphorylation PhosphoSitePlus
K99 Sumoylation PhosphoSitePlus
S131 Phosphorylation PhosphoSitePlus
S139 Phosphorylation PhosphoSitePlus
T142 Phosphorylation PhosphoSitePlus
T161 Phosphorylation PhosphoSitePlus
S165 Phosphorylation PhosphoSitePlus
S182 Phosphorylation PhosphoSitePlus
S184 Phosphorylation PhosphoSitePlus
T187 Phosphorylation PhosphoSitePlus
T188 Phosphorylation PhosphoSitePlus
S193 Phosphorylation PhosphoSitePlus
S203 Phosphorylation PhosphoSitePlus
S213 Phosphorylation P27361 (MAPK3) HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   UniProt 21406692, 18212344, 15060146, ...20166139, 20068231
S238 Phosphorylation PhosphoSitePlus
S257 Phosphorylation P27361 (MAPK3) , Q16539 (MAPK14) neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 15060146, 18022807, 12435397
S271 Phosphorylation PhosphoSitePlus
S284 Phosphorylation PhosphoSitePlus
S293 Phosphorylation PhosphoSitePlus
K302 Acetylation PhosphoSitePlus   UniProt 19608861
K302 Ubiquitination PhosphoSitePlus
Y314 Phosphorylation PhosphoSitePlus
S323 Phosphorylation PhosphoSitePlus
K384 Ubiquitination PhosphoSitePlus
K393 Ubiquitination PhosphoSitePlus
Y401 Phosphorylation PhosphoSitePlus
Y402 Phosphorylation PhosphoSitePlus
K403 Ubiquitination PhosphoSitePlus
K421 Sumoylation PhosphoSitePlus
K421 Ubiquitination PhosphoSitePlus
T422 Phosphorylation PhosphoSitePlus
S439 Phosphorylation PhosphoSitePlus
Y447 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S2 C2 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
T4 I4 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K11 * Biomuta DOID:2531 / hematologic cancer [ cosmic ]
K11 N11 Biomuta DOID:5041 / esophageal cancer [ cosmic ] DOID:2531 / hematologic cancer [ cosmic, icgc ]
S16 L16 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic ]
S16 * Biomuta DOID:5041 / esophageal cancer [ cosmic ]
S22 C22 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
S22 R22 Biomuta DOID:10534 / stomach cancer [ cosmic ]
S29 F29 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S30 L30 Biomuta DOID:1324 / lung cancer [ cosmic ]
S47 L47 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S139 F139 Biomuta DOID:4159 / skin cancer [ cosmic ]
S165 C165 Biomuta DOID:11054 / urinary bladder cancer [ cosmic ]
S184 T184 Biomuta DOID:9256 / colorectal cancer [ cosmic, icgc ]
S213 F213 Biomuta DOID:4159 / skin cancer [ cosmic ]
S238 Y238 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S271 T271 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S284 F284 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K393 I393 Biomuta DOID:4606 / bile duct cancer [ cosmic ]
Y401 C401 Biomuta [ cosmic ] DOID:2531 / hematologic cancer [ cosmic ]
Y402 C402 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:1324 / lung cancer [ cosmic ]
K403 E403 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
K403 N403 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S439 C439 Biomuta DOID:3119 / gastrointestinal system cancer [ cosmic ]
S439 F439 Biomuta [ cosmic ]