iPTMnet Report for P41182 (BCL6)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P41182 / BCL6_HUMAN
Protein Name B-cell lymphoma 6 protein
Gene Name Name: BCL6
Synonyms:BCL5,LAZ3,ZBTB27,ZNF51;
Organism Homo sapiens (Human)

PRO ID PR:P41182
DAG View
PRO Name B-cell lymphoma 6 protein (human)
Definition A B-cell lymphoma 6 protein that is encoded in the genome of human.
Short Label hBCL6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P41182 (BCL6) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S3 Phosphorylation PhosphoSitePlus
Y157 Phosphorylation PhosphoSitePlus
S256 Phosphorylation PhosphoSitePlus
S260 Phosphorylation PhosphoSitePlus
K282 Ubiquitination PhosphoSitePlus
K298 Ubiquitination PhosphoSitePlus
R305 Methylation PhosphoSitePlus
S307 Phosphorylation PhosphoSitePlus
S308 Phosphorylation PhosphoSitePlus
S330 Phosphorylation PhosphoSitePlus
S333 Phosphorylation P28482 (MAPK1) , P27361 (MAPK3) neXtProt   PhosphoSitePlus   Signor   UniProt 9649500, 23186163
S337 Phosphorylation PhosphoSitePlus
S343 Phosphorylation P27361 (MAPK3) , P28482 (MAPK1) neXtProt   PhosphoSitePlus   Signor   UniProt 9649500
S359 Phosphorylation PhosphoSitePlus
S361 Phosphorylation PhosphoSitePlus
K371 Ubiquitination PhosphoSitePlus
K379 Acetylation PhosphoSitePlus   UniProt 12402037
S385 Phosphorylation PhosphoSitePlus
S404 Phosphorylation PhosphoSitePlus
S427 Phosphorylation PhosphoSitePlus
S466 Phosphorylation PhosphoSitePlus
T569 Phosphorylation PhosphoSitePlus
K572 Ubiquitination PhosphoSitePlus
Y574 Phosphorylation PhosphoSitePlus
S597 Phosphorylation PhosphoSitePlus
T625 Phosphorylation PhosphoSitePlus
T653 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S308 Phosphorylation HPRD 18452278


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S3 L3 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic ]
S260 L260 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
R305 I305 Biomuta DOID:184 / bone cancer [ cosmic ]
S330 C330 Biomuta DOID:4159 / skin cancer [ cosmic ]
S359 F359 Biomuta DOID:1324 / lung cancer [ cosmic ]
S361 F361 Biomuta DOID:4362 / cervical cancer [ cosmic ]
S404 F404 Biomuta DOID:4159 / skin cancer [ cosmic ]
S597 C597 Biomuta DOID:1781 / thyroid gland cancer [ cosmic ] DOID:1781 / thyroid cancer [ icgc ]
T625 S625 Biomuta DOID:1324 / lung cancer [ cosmic ]