iPTMnet Report for P41162 (ETV3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P41162 / ETV3_HUMAN
Protein Name ETS translocation variant 3
Gene Name Name: ETV3
Synonyms:METS,PE1;
Organism Homo sapiens (Human)

PRO ID PR:P41162
DAG View
PRO Name ETS translocation variant 3 (human)
Definition An ETS translocation variant 3 that is encoded in the genome of human.
Short Label hETV3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P41162 (ETV3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K2 Ubiquitination PhosphoSitePlus
S6 Phosphorylation PhosphoSitePlus
K10 Ubiquitination PhosphoSitePlus
Y17 Phosphorylation PhosphoSitePlus
K25 Ubiquitination PhosphoSitePlus
K80 Ubiquitination PhosphoSitePlus
K82 Ubiquitination PhosphoSitePlus
K89 Ubiquitination PhosphoSitePlus
K114 Ubiquitination PhosphoSitePlus
S133 Phosphorylation PhosphoSitePlus
S139 Phosphorylation P28482 (MAPK1) neXtProt   PhosphoSitePlus   UniProt 22028470, 23186163, 19690332
T157 Phosphorylation PhosphoSitePlus
S159 Phosphorylation PhosphoSitePlus   UniProt 23186163
T161 Phosphorylation PhosphoSitePlus
K188 Ubiquitination PhosphoSitePlus
K224 Ubiquitination PhosphoSitePlus
Y240 Phosphorylation PhosphoSitePlus
S245 Phosphorylation PhosphoSitePlus
S250 Phosphorylation PhosphoSitePlus
S264 Phosphorylation PhosphoSitePlus
S315 Phosphorylation PhosphoSitePlus
T318 Phosphorylation PhosphoSitePlus
S361 Phosphorylation PhosphoSitePlus
S362 Phosphorylation PhosphoSitePlus
T370 Phosphorylation PhosphoSitePlus
T372 Phosphorylation PhosphoSitePlus
K381 Sumoylation PhosphoSitePlus
K388 Acetylation PhosphoSitePlus   UniProt 19608861
T404 Phosphorylation PhosphoSitePlus
K419 Ubiquitination PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K2 T2 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K10 E10 Biomuta DOID:1324 / lung cancer [ cosmic ]
K80 E80 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
K89 * Biomuta DOID:10283 / prostate cancer [ cosmic ]
K188 T188 Biomuta DOID:9256 / colorectal cancer [ icgc ]
S362 R362 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
T370 M370 Biomuta DOID:1324 / lung cancer [ cosmic ]