Protein Information

Cytoscape View


UniProt AC / UniProt ID P41159 / LEP_HUMAN
Protein Name Leptin precursor
Gene Name Name: LEP
Synonyms:OB;
Organism Homo sapiens (Human)

PRO ID PR:P41159
DAG View
PRO Name leptin (human)
Definition A leptin that is encoded in the genome of human.
Short Label hLEP
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P41159 (LEP) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T48 Phosphorylation PhosphoSitePlus


PTM-dependent PPI

PTM type Substrate Site Interactant Association type Source PMID
Phosphorylation P35968 (KDR) Y1175 P41159 (LEP) unknown eFIP 21533119


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T48 M48 Biomuta DOID:3571 / liver cancer [ tcga ]