iPTMnet Report for P41159 (LEP)
Protein Information
UniProt AC / UniProt ID | P41159 / LEP_HUMAN |
Protein Name | Leptin precursor |
Gene Name | Name: LEP Synonyms:OB; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P41159 |
PRO Name | leptin (human) |
Definition | A leptin that is encoded in the genome of human. |
Short Label | hLEP |
Category | organism-gene |
P41159 (LEP) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
T48 | Phosphorylation | score1 | PhosphoSitePlus |
PTM-dependent PPI
PTM type | Substrate | Site | Interactant | Association type | Source | PMID | |
---|---|---|---|---|---|---|---|
Phosphorylation | P35968 (KDR) | Y1175 | P41159 (LEP) | unknown | eFIP | 21533119 |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
T48 | M48 | Biomuta | DOID:3571 / liver cancer [ cosmic, icgc ] |