iPTMnet Report for P40938 (RFC3)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P40938 / RFC3_HUMAN
Protein Name Replication factor C subunit 3
Gene Name Name: RFC3
Organism Homo sapiens (Human)

PRO ID PR:P40938
DAG View
PRO Name replication factor C subunit 3 (human)
Definition A replication factor C subunit 3 that is encoded in the genome of human.
Short Label hRFC3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P40938 (RFC3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Phosphorylation PhosphoSitePlus
K7 Methylation PhosphoSitePlus
K7 Ubiquitination PhosphoSitePlus
S12 Phosphorylation PhosphoSitePlus
K20 Acetylation PhosphoSitePlus   UniProt 19608861
K20 Ubiquitination PhosphoSitePlus
C32 Methylation IEDB 31844290
K48 Ubiquitination PhosphoSitePlus
C54 Methylation IEDB 31844290
Y60 Phosphorylation PhosphoSitePlus
K66 Ubiquitination PhosphoSitePlus
T75 Phosphorylation PhosphoSitePlus
T76 Phosphorylation PhosphoSitePlus
K79 Ubiquitination PhosphoSitePlus
Y91 Phosphorylation PhosphoSitePlus
K113 Ubiquitination PhosphoSitePlus
T123 Phosphorylation PhosphoSitePlus
S125 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17525332
K130 Ubiquitination PhosphoSitePlus
K139 Ubiquitination PhosphoSitePlus
K142 Ubiquitination PhosphoSitePlus
K154 Ubiquitination PhosphoSitePlus
C159 Methylation IEDB 31844290
K170 Ubiquitination PhosphoSitePlus
C193 Methylation IEDB 31844290
K201 Ubiquitination PhosphoSitePlus
K202 Ubiquitination PhosphoSitePlus
S209 Phosphorylation PhosphoSitePlus
K218 Ubiquitination PhosphoSitePlus
C220 Methylation IEDB 31844290
K225 Ubiquitination PhosphoSitePlus
T283 Phosphorylation PhosphoSitePlus
Y343 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y60 Phosphorylation HPRD 20068231
S125 Phosphorylation HPRD 17525332
Site PTM Type PTM Enzyme Score Source PMID
Y60 Phosphorylation HPRD 20068231
S125 Phosphorylation HPRD 17525332


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S12 T12 Biomuta DOID:263 / kidney cancer [ cosmic ]
Y60 H60 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, cosmic ]
K142 R142 Biomuta DOID:1324 / lung cancer [ cosmic ]
K201 E201 Biomuta DOID:263 / kidney cancer [ cosmic ]
K202 R202 Biomuta DOID:5041 / esophageal cancer [ cosmic, icgc ]
C220 F220 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
Y343 H343 Biomuta DOID:1324 / lung cancer [ cosmic ]