iPTMnet Report for P40926 (MDH2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P40926 / MDHM_HUMAN
Protein Name Malate dehydrogenase, mitochondrial precursor
Gene Name Name: MDH2
Organism Homo sapiens (Human)

PRO ID PR:P40926
DAG View
PRO Name malate dehydrogenase, mitochondrial (human)
Definition A malate dehydrogenase, mitochondrial that is encoded in the genome of human.
Short Label hMDH2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P40926 (MDH2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S18 Phosphorylation PhosphoSitePlus
K26 Acetylation PhosphoSitePlus
S33 Phosphorylation PhosphoSitePlus
S41 Phosphorylation PhosphoSitePlus
S51 Phosphorylation PhosphoSitePlus
Y56 Phosphorylation phospho.ELM   PhosphoSitePlus 15592455
T61 Phosphorylation PhosphoSitePlus
S69 Phosphorylation PhosphoSitePlus
K74 Acetylation PhosphoSitePlus
K74 Ubiquitination PhosphoSitePlus
K78 Acetylation PhosphoSitePlus
K78 Ubiquitination PhosphoSitePlus
Y80 Phosphorylation PhosphoSitePlus
K91 Acetylation PhosphoSitePlus
K91 Ubiquitination PhosphoSitePlus
K156 Acetylation PhosphoSitePlus
K157 Acetylation PhosphoSitePlus
K157 Ubiquitination PhosphoSitePlus
Y161 Phosphorylation PhosphoSitePlus
K165 Acetylation IEDB   PhosphoSitePlus   UniProt 34357683, 19608861
T170 Phosphorylation PhosphoSitePlus
T171 Phosphorylation PhosphoSitePlus
T179 Phosphorylation PhosphoSitePlus
K185 Acetylation PhosphoSitePlus   UniProt 19608861, 20167786
K185 Ubiquitination PhosphoSitePlus
K203 Acetylation PhosphoSitePlus
K203 Ubiquitination PhosphoSitePlus
T204 Phosphorylation PhosphoSitePlus
C212 S-Nitrosylation dbSNO 19483679
T213 Phosphorylation PhosphoSitePlus
K215 Acetylation PhosphoSitePlus
T224 Phosphorylation PhosphoSitePlus
T227 Phosphorylation PhosphoSitePlus
T235 Phosphorylation PhosphoSitePlus
K239 Acetylation PhosphoSitePlus
K239 Ubiquitination PhosphoSitePlus
K241 Ubiquitination PhosphoSitePlus
S246 Phosphorylation PhosphoSitePlus   UniProt 23186163
T248 Phosphorylation PhosphoSitePlus
Y253 Phosphorylation PhosphoSitePlus
R257 Methylation PhosphoSitePlus
S261 Phosphorylation PhosphoSitePlus
C275 Methylation IEDB 31844290
S276 O-Glycosylation GlyGen 16408927, 30444036, 30397120, ...34725712, 33214551, 29351928, 34019948, 35083852, 32119511, 28510447
S276 Phosphorylation PhosphoSitePlus
S280 Phosphorylation PhosphoSitePlus
T283 Phosphorylation PhosphoSitePlus
C285 S-Nitrosylation dbSNO 19483679, 26338901
T286 Phosphorylation PhosphoSitePlus
Y287 Phosphorylation PhosphoSitePlus
K296 Acetylation PhosphoSitePlus
K296 Ubiquitination PhosphoSitePlus
K297 Acetylation PhosphoSitePlus
K297 Ubiquitination PhosphoSitePlus
K301 Acetylation PhosphoSitePlus   UniProt 19608861, 20167786
K301 Ubiquitination PhosphoSitePlus
K307 Acetylation PhosphoSitePlus   UniProt 20167786
K307 Ubiquitination PhosphoSitePlus
S309 Phosphorylation IEDB 32387766
S310 Phosphorylation PhosphoSitePlus
K314 Acetylation PhosphoSitePlus   UniProt 19608861, 20167786
K314 Ubiquitination PhosphoSitePlus
S317 Phosphorylation PhosphoSitePlus
K324 Acetylation PhosphoSitePlus
S326 Phosphorylation PhosphoSitePlus   UniProt 23186163
K328 Acetylation PhosphoSitePlus
K329 Acetylation PhosphoSitePlus   UniProt 19608861
K335 Acetylation PhosphoSitePlus   UniProt 19608861
K335 Ubiquitination PhosphoSitePlus
T336 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y56 Phosphorylation HPRD 15592455
T171 Phosphorylation HPRD 20068231
T283 Phosphorylation HPRD 20068230
Y287 Phosphorylation HPRD 20068230