iPTMnet Report for P40855 (PEX19)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P40855 / PEX19_HUMAN
Protein Name Peroxisomal biogenesis factor 19 precursor
Gene Name Name: PEX19
Synonyms:HK33,PXF;ORFNames:OK/SW-cl.22;
Organism Homo sapiens (Human)

PRO ID PR:P40855
DAG View
PRO Name peroxisomal biogenesis factor 19 (human)
Definition A peroxisomal biogenesis factor 19 that is encoded in the genome of human.
Short Label hPEX19
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P40855 (PEX19) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22814378, 25944712
S9 Phosphorylation PhosphoSitePlus
K33 Ubiquitination PhosphoSitePlus
S35 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17287340, 23186163, 24275569
S40 Phosphorylation PhosphoSitePlus
T42 O-Glycosylation GlyGen 23301498, 30379171, 28510447, ...29237092
T42 Phosphorylation PhosphoSitePlus
K52 Ubiquitination PhosphoSitePlus
S54 O-Glycosylation GlyGen 23301498, 30379171, 28510447, ...29237092
S54 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18669648, 17287340
T58 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648
K60 Ubiquitination PhosphoSitePlus
S66 Phosphorylation PhosphoSitePlus
K69 Ubiquitination PhosphoSitePlus
K89 Ubiquitination PhosphoSitePlus
K92 Ubiquitination PhosphoSitePlus
K107 Ubiquitination PhosphoSitePlus
S117 Phosphorylation PhosphoSitePlus
C128 Methylation IEDB 31844290
K130 Ubiquitination PhosphoSitePlus
S134 Phosphorylation PhosphoSitePlus
K138 Ubiquitination PhosphoSitePlus
T141 Phosphorylation PhosphoSitePlus
S146 Phosphorylation phospho.ELM   PhosphoSitePlus 17287340
S147 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 17287340
S149 Phosphorylation phospho.ELM   PhosphoSitePlus 18669648, 17287340
S177 Phosphorylation phospho.ELM   PhosphoSitePlus 17287340
S184 Phosphorylation phospho.ELM 17287340
K193 Ubiquitination PhosphoSitePlus
K198 Ubiquitination PhosphoSitePlus
Y199 Phosphorylation PhosphoSitePlus
T236 Phosphorylation PhosphoSitePlus
K245 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S35 Phosphorylation HPRD 17287340
S40 Phosphorylation HPRD 20068231
T41 Phosphorylation HPRD 20068231
T42 Phosphorylation HPRD 20068231
S54 Phosphorylation HPRD 19413330, 18669648, 17287340
T58 Phosphorylation HPRD 18669648
S117 Phosphorylation HPRD 18452278
S134 Phosphorylation HPRD 18452278
S146 Phosphorylation HPRD 19413330, 19651622, 17287340, ...20068231
S147 Phosphorylation HPRD 19413330, 17287340, 18767875, ...19664995, 18452278, 19651622, 18669648, 19415658, 20068231
S149 Phosphorylation HPRD 19413330, 17287340, 19664994, ...18452278, 19651622, 18669648, 20068231
S177 Phosphorylation HPRD 17287340


Proteoform PPIs

Protein 1 Relation Protein 2 Source PMID
PR:P40855-1 (hPEX19/iso:1) Interaction PR:Q9Y5Y5 (hPEX16) PRO 15713480
PR:P40855-1 (hPEX19/iso:1) Interaction PR:P33897 (hABCD1) PRO 11883941
PR:P40855-1 (hPEX19/iso:1) Interaction PR:Q9UBJ2 (hABCD2) PRO 11883941
PR:P40855-1 (hPEX19/iso:1) Interaction PR:P28288 (hABCD3) PRO 11883941
PR:P40855-1 (hPEX19/iso:1) Interaction PR:P56589 (hPEX3) PRO 11883941
PR:P40855-1 (hPEX19/iso:1) Interaction PR:Q7Z412 (hPEX26) PRO 15713480
PR:P40855-2 (hPEX19/iso:2) Interaction PR:Q9UBJ2 (hABCD2) PRO 11883941
PR:P40855-2 (hPEX19/iso:2) Interaction PR:P56589 (hPEX3) PRO 11883941
PR:P40855-2 (hPEX19/iso:2) Interaction PR:P28288 (hABCD3) PRO 11883941
PR:P40855-2 (hPEX19/iso:2) Interaction PR:P33897 (hABCD1) PRO 11883941
PR:P40855-4 (hPEX19/iso:4) Interaction PR:P33897 (hABCD1) PRO 11883941
PR:P40855-4 (hPEX19/iso:4) Interaction PR:Q9UBJ2 (hABCD2) PRO 11883941
PR:P40855-4 (hPEX19/iso:4) Interaction PR:P56589 (hPEX3) PRO 11883941
PR:P40855-4 (hPEX19/iso:4) Interaction PR:P28288 (hABCD3) PRO 11883941


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S40 F40 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
S54 L54 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
S66 A66 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K130 N130 Biomuta DOID:1324 / lung cancer [ cosmic ]
S134 N134 Biomuta DOID:2531 / hematologic cancer [ cosmic, icgc ]
S149 L149 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
T236 N236 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]