iPTMnet Report for P40692 (MLH1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P40692 / MLH1_HUMAN
Protein Name DNA mismatch repair protein Mlh1
Gene Name Name: MLH1
Synonyms:COCA2;
Organism Homo sapiens (Human)

PRO ID PR:P40692
DAG View
PRO Name DNA mismatch repair protein Mlh1 (human)
Definition A DNA mismatch repair protein Mlh1 that is encoded in the genome of human.
Short Label hMLH1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P40692 (MLH1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S2 Acetylation UniProt 22223895
S2 Phosphorylation PhosphoSitePlus
K33 Ubiquitination PhosphoSitePlus
K57 Ubiquitination PhosphoSitePlus
K70 Ubiquitination PhosphoSitePlus
K84 Ubiquitination PhosphoSitePlus
S87 Phosphorylation PhosphoSitePlus
K123 Ubiquitination PhosphoSitePlus
K134 Ubiquitination PhosphoSitePlus
K140 Ubiquitination PhosphoSitePlus
K164 Ubiquitination PhosphoSitePlus
K167 Ubiquitination PhosphoSitePlus
K175 Ubiquitination PhosphoSitePlus
Y183 Phosphorylation PhosphoSitePlus
K196 Ubiquitination PhosphoSitePlus
T212 Phosphorylation PhosphoSitePlus
K236 Ubiquitination PhosphoSitePlus
K241 Ubiquitination PhosphoSitePlus
T288 Phosphorylation PhosphoSitePlus
Y293 Phosphorylation PhosphoSitePlus
S295 Phosphorylation PhosphoSitePlus
K333 Ubiquitination PhosphoSitePlus
K361 Ubiquitination PhosphoSitePlus
T363 O-Glycosylation GlyGen 30379171, 28411811, 32574038, ...35132862, 30059200
S370 Phosphorylation PhosphoSitePlus
K377 Ubiquitination PhosphoSitePlus
Y379 Phosphorylation PhosphoSitePlus
T386 Phosphorylation PhosphoSitePlus
S388 Phosphorylation PhosphoSitePlus
K392 Sumoylation PhosphoSitePlus
K392 Ubiquitination PhosphoSitePlus
K402 Acetylation PhosphoSitePlus
K402 Ubiquitination PhosphoSitePlus
S406 Phosphorylation Q13315 (ATM) , Q13535 (ATR) PhosphoSitePlus   RLIMS-P 21864706
K416 Sumoylation PhosphoSitePlus
K416 Ubiquitination PhosphoSitePlus
K443 Acetylation PhosphoSitePlus
K443 Ubiquitination PhosphoSitePlus
S446 Phosphorylation PhosphoSitePlus
K453 Ubiquitination PhosphoSitePlus
S459 Phosphorylation PhosphoSitePlus
K461 Acetylation PhosphoSitePlus
S467 Phosphorylation PhosphoSitePlus
S477 Phosphorylation phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 21406692, 23186163, 30136313, ...18669648, 24275569, 19690332
S486 Phosphorylation PhosphoSitePlus
K488 Ubiquitination PhosphoSitePlus
T495 Phosphorylation PhosphoSitePlus
S508 Phosphorylation PhosphoSitePlus
K688 Ubiquitination PhosphoSitePlus
K732 Ubiquitination PhosphoSitePlus
K751 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
Y183 Phosphorylation HPRD 20068231
S184 Phosphorylation HPRD 20068231
S269 Phosphorylation HPRD 20068231
S477 Phosphorylation HPRD 18669648, 20068231