iPTMnet Report for P40261 (NNMT)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P40261 / NNMT_HUMAN
Protein Name Nicotinamide N-methyltransferase
Gene Name Name: NNMT
Organism Homo sapiens (Human)

PRO ID PR:P40261
DAG View
PRO Name nicotinamide N-methyltransferase (human)
Definition A nicotinamide N-methyltransferase that is encoded in the genome of human.
Short Label hNNMT
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P40261 (NNMT) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation PRO
S3 Phosphorylation PhosphoSitePlus
K8 Acetylation PhosphoSitePlus
K8 Methylation PhosphoSitePlus
K8 Ubiquitination PhosphoSitePlus
Y11 Phosphorylation PhosphoSitePlus
K23 Ubiquitination PhosphoSitePlus
Y24 Phosphorylation PhosphoSitePlus
Y25 Phosphorylation PhosphoSitePlus
K26 Ubiquitination PhosphoSitePlus
S35 Phosphorylation PhosphoSitePlus
K39 Acetylation PhosphoSitePlus   UniProt 19608861
K39 Ubiquitination PhosphoSitePlus
K43 Acetylation PhosphoSitePlus
K43 Ubiquitination PhosphoSitePlus
K47 Ubiquitination PhosphoSitePlus
K96 Ubiquitination PhosphoSitePlus
K100 Ubiquitination PhosphoSitePlus
S108 Phosphorylation PhosphoSitePlus
Y113 Phosphorylation PhosphoSitePlus
K123 Ubiquitination PhosphoSitePlus
K136 Ubiquitination PhosphoSitePlus
Y203 Phosphorylation PhosphoSitePlus
Y204 Phosphorylation PhosphoSitePlus
K210 Ubiquitination PhosphoSitePlus


Proteoforms

PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000036304 (hNNMT/Ac:1) acM1 PRO


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K26 R26 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K47 N47 Biomuta DOID:363 / uterine cancer [ icgc ]
S108 P108 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]