iPTMnet Report for P40059 (DOT6)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P40059 / DOT6_YEAST
Protein Name Transcriptional regulatory protein DOT6
Gene Name Name: DOT6
Synonyms:PBF2;OrderedLocusNames:YER088C;
Organism Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

PRO ID PR:P40059
DAG View
PRO Name transcriptional regulatory protein DOT6 (yeast)
Definition A protein that is a translation product of the DOT6 gene in yeast.
Short Label yDOT6
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P40059 (DOT6) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S45 Phosphorylation SGD 23749301
S46 Phosphorylation BioGRID   SGD 19779198
K70 Acetylation SGD 22865919
S73 Phosphorylation SGD 23749301
S74 Phosphorylation SGD 23749301
K139 Acetylation SGD 22865919
K156 Ubiquitination SGD 23749301
T163 Phosphorylation SGD 23749301
S179 Phosphorylation SGD 23749301
S183 Phosphorylation SGD 33491328
S245 Phosphorylation BioGRID   SGD   UniProt 30516470, 33481703, 24909858, ...21177495, 20702584, 23749301, 22218487, 19779198, 32597660, 33491328
S247 Phosphorylation BioGRID   SGD   UniProt 23749301, 33481703, 17330950, ...24909858, 20702584, 17287358, 19779198, 32597660, 19684113, 21177495, 33491328
S249 Phosphorylation BioGRID   SGD 17330950, 19684113, 21177495, ...23749301, 33491328
T251 Phosphorylation BioGRID   SGD 17330950, 24909858, 22218487, ...19779198, 21177495, 23749301
S253 Phosphorylation SGD 23749301
S281 Phosphorylation SGD 19779198, 23749301
S282 Phosphorylation BioGRID   SGD 17330950, 19779198, 21177495, ...23749301, 19684113
Y285 Phosphorylation BioGRID   SGD 21177495, 23749301
T292 Phosphorylation BioGRID   SGD 19779198, 21177495, 23749301
T293 Phosphorylation BioGRID   SGD 19779198, 21177495, 23749301
T294 Phosphorylation BioGRID   SGD 19684113, 21177495, 23749301, ...19779198
S296 Phosphorylation BioGRID   SGD 17330950, 19779198, 21177495, ...23749301, 19684113
S297 Phosphorylation BioGRID   SGD 21177495, 19779198, 33481703, ...33491328, 23749301
S300 Phosphorylation BioGRID   SGD 19779198, 21177495, 23749301
S301 Phosphorylation BioGRID   SGD 21177495, 23749301
S306 Phosphorylation BioGRID 21177495
S309 Phosphorylation SGD 24909858, 23749301
S313 Phosphorylation BioGRID   SGD 30516470, 33481703, 32597660, ...33491328, 19779198, 19684113, 21177495, 23749301
S318 Phosphorylation BioGRID   SGD 33481703, 24909858, 22218487, ...19779198, 19684113, 21177495, 23749301
S321 Phosphorylation SGD 33481703
S322 Phosphorylation BioGRID   SGD 30516470, 21177495, 23749301, ...19779198, 32597660, 33491328
S326 Phosphorylation BioGRID   SGD 21177495, 23749301, 33481703
S327 Phosphorylation BioGRID   SGD 19779198, 32597660, 23749301, ...33481703, 30516470
T330 Phosphorylation BioGRID   SGD 19779198, 21177495, 33481703
S331 Phosphorylation BioGRID   SGD 21177495, 33481703
S352 Phosphorylation SGD 23749301
S354 Phosphorylation SGD 23749301
T359 Phosphorylation SGD 23749301
S360 Phosphorylation SGD 23749301
T362 Phosphorylation SGD 23749301
S368 Phosphorylation SGD 32597660
S398 Phosphorylation SGD 23749301
S409 Phosphorylation SGD 23749301
S411 Phosphorylation SGD 23749301
S412 Phosphorylation SGD 23749301
S413 Phosphorylation SGD 23749301
S419 Phosphorylation SGD 23749301
S423 Phosphorylation BioGRID   SGD 30516470, 21177495, 23749301, ...19779198, 32597660, 33491328
S425 Phosphorylation SGD 33491328
S428 Phosphorylation BioGRID   SGD 21177495, 23749301
S456 Phosphorylation SGD 24909858, 23749301
S480 Phosphorylation BioGRID   SGD 19779198
S481 Phosphorylation BioGRID   SGD 19779198, 21177495, 23749301, ...18407956, 33491328
S487 Phosphorylation P24869 (CLB2) , P00546 (CDC28) BioGRID   SGD   UniProt 30516470, 33481703, 17330950, ...24909858, 21177495, 20702584, 23749301, 22218487, 19779198, 19684113, 32597660, 33491328
T489 Phosphorylation BioGRID   SGD   UniProt 33481703, 24909858, 20702584, ...33491328, 19779198, 21177495, 23749301
S491 Phosphorylation P00546 (CDC28) , P24869 (CLB2) BioGRID   SGD   UniProt 30516470, 33481703, 17330950, ...24909858, 20702584, 18407956, 23749301, 21177495, 19779198, 19684113, 32597660, 33491328
S507 Phosphorylation BioGRID   SGD 19779198, 32597660
S509 Phosphorylation BioGRID   SGD 19779198
T511 Phosphorylation BioGRID   SGD 19779198
S517 Phosphorylation BioGRID   SGD 21177495, 19779198, 30516470, ...33491328
S527 Phosphorylation BioGRID   SGD 19779198, 21177495, 33491328
T548 Phosphorylation BioGRID 21126336
S551 Phosphorylation SGD 23749301
S553 Phosphorylation SGD 33481703, 33491328, 18407956, ...23749301
S554 Phosphorylation SGD 33491328
S555 Phosphorylation SGD 33481703, 18407956, 33491328
S558 Phosphorylation SGD 33481703, 33491328, 18407956, ...23749301
S559 Phosphorylation SGD 33481703, 33491328, 23749301
S563 Phosphorylation BioGRID   SGD 30516470, 33481703, 24909858, ...23749301, 22218487, 19779198, 33491328
S569 Phosphorylation SGD 23749301, 33481703
T579 Phosphorylation BioGRID 21177495
S580 Phosphorylation SGD 23749301, 33491328
S590 Phosphorylation SGD 23749301, 33491328
T592 Phosphorylation SGD 23749301
S593 Phosphorylation SGD 33491328
S594 Phosphorylation SGD 23749301
T598 Phosphorylation SGD 23749301, 33491328
T602 Phosphorylation SGD 23749301, 33491328
S605 Phosphorylation SGD 33491328
K606 Acetylation SGD 22865919
K606 Ubiquitination SGD 23749301
T623 Phosphorylation SGD 34965436