iPTMnet Report for P39086 (GRIK1)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P39086 / GRIK1_HUMAN
Protein Name Glutamate receptor ionotropic, kainate 1 precursor
Gene Name Name: GRIK1
Synonyms:GLUR5;
Organism Homo sapiens (Human)

PRO ID PR:P39086
DAG View
PRO Name glutamate receptor ionotropic, kainate 1 (human)
Definition A glutamate receptor ionotropic, kainate 1 that is encoded in the genome of human.
Short Label hGRIK1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P39086 (GRIK1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
K386 Methylation PhosphoSitePlus
K396 Methylation PhosphoSitePlus
S487 Phosphorylation PhosphoSitePlus
Y494 Phosphorylation PhosphoSitePlus
S681 Phosphorylation PhosphoSitePlus
S685 Phosphorylation PhosphoSitePlus
S704 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S879 Phosphorylation PhosphoSitePlus
S885 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K386 N386 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
K386 E386 Biomuta DOID:363 / uterine cancer [ icgc ]
S681 F681 Biomuta DOID:4159 / skin cancer [ cosmic ]
S685 L685 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:10283 / prostate cancer [ cosmic ] DOID:10534 / stomach cancer [ cosmic ] DOID:9256 / colorectal cancer [ cosmic, icgc ]
S879 * Biomuta DOID:1612 / breast cancer [ cosmic ]