Protein Information

Cytoscape View


UniProt AC / UniProt ID P39060 / COIA1_HUMAN
Protein Name Collagen alpha-1(XVIII) chain precursor
Gene Name Name: COL18A1
Organism Homo sapiens (Human)

PRO ID PR:P39060
DAG View
PRO Name collagen alpha-1(XVIII) chain (human)
Definition A collagen alpha-1(XVIII) chain that is encoded in the genome of human.
Short Label hCOL18A1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P39060 (COL18A1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T43 O-Glycosylation GlyGen 30459171
S79 O-Glycosylation GlyGen 30459171
T93 O-Glycosylation GlyGen 30459171
T93 Phosphorylation PhosphoSitePlus
T95 O-Glycosylation GlyGen 30459171
S96 O-Glycosylation GlyGen 30459171
S99 Phosphorylation PhosphoSitePlus
N129 N-Glycosylation GlyGen 29741879
T192 O-Glycosylation GlyGen 30459171
S194 O-Glycosylation GlyGen 30459171
T472 O-Glycosylation GlyGen 30459171
T474 O-Glycosylation GlyGen 30459171
T696 O-Glycosylation GlyGen 30459171
T696 Phosphorylation PhosphoSitePlus   UniProt 24275569
T697 O-Glycosylation GlyGen 30459171
T697 Phosphorylation PhosphoSitePlus
S704 Phosphorylation PhosphoSitePlus
S705 Phosphorylation PhosphoSitePlus
T706 Phosphorylation PhosphoSitePlus
S709 Phosphorylation PhosphoSitePlus
S711 Phosphorylation PhosphoSitePlus
T718 O-Glycosylation GlyGen 30459171
T719 O-Glycosylation GlyGen 30459171
T727 O-Glycosylation GlyGen 30459171
S731 O-Glycosylation GlyGen 30459171
S733 O-Glycosylation GlyGen 30459171
S735 O-Glycosylation GlyGen 30459171
T736 O-Glycosylation GlyGen 30459171
T799 O-Glycosylation GlyGen 30459171
S889 O-Glycosylation GlyGen   UniProt 32337544
R902 Methylation PhosphoSitePlus
Y1211 Phosphorylation PhosphoSitePlus
S1245 Phosphorylation PhosphoSitePlus
S1443 O-Glycosylation GlyGen 34019948, 29351928
T1450 Phosphorylation PhosphoSitePlus
T1527 O-Glycosylation GlyGen   PhosphoSitePlus 23584533
S1539 O-Glycosylation GlyGen   PhosphoSitePlus 23584533, 30459171
S1556 O-Glycosylation GlyGen 30459171
T1567 O-Glycosylation GlyGen   IEDB 10441114, 30459171, 27550523
S1588 Phosphorylation PhosphoSitePlus
K1666 Ubiquitination PhosphoSitePlus
K1677 Ubiquitination PhosphoSitePlus
T1711 O-Glycosylation GlyGen 30459171
T1717 O-Glycosylation GlyGen 30459171


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T95 I95 Biomuta DOID:8618 / oral cavity cancer [ cosmic ] DOID:11934 / head and neck cancer [ icgc ]
T472 I472 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
T474 M474 Biomuta DOID:1793 / pancreatic cancer [ cosmic ] DOID:1612 / breast cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic ]
T719 S719 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
T1711 M1711 Biomuta DOID:1793 / pancreatic cancer [ cosmic ]
T1717 M1717 Biomuta DOID:4606 / bile duct cancer [ cosmic ]