Protein Information

Cytoscape View


UniProt AC / UniProt ID P39023 / RL3_HUMAN
Protein Name 60S ribosomal protein L3
Gene Name Name: RPL3
ORFNames:OK/SW-cl.32;
Organism Homo sapiens (Human)

PRO ID PR:P39023
DAG View
PRO Name 60S ribosomal protein L3 (human)
Definition A 60S ribosomal protein L3 that is encoded in the genome of human.
Short Label hRPL3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P39023 (RPL3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S7 Phosphorylation HPRD   PhosphoSitePlus 18691976, 20068231
S13 Phosphorylation HPRD   PhosphoSitePlus   UniProt 19369195, 23186163, 18767875, ...18669648, 20068231
R19 Methylation PhosphoSitePlus
K39 Ubiquitination PhosphoSitePlus
T54 Phosphorylation HPRD   PhosphoSitePlus 20068231
S65 Phosphorylation PhosphoSitePlus
K66 Ubiquitination PhosphoSitePlus
K103 Acetylation PhosphoSitePlus
C114 S-Nitrosylation dbSNO 2212679, 22126794, 26338901
K115 Acetylation PhosphoSitePlus
K115 Ubiquitination PhosphoSitePlus
K120 Ubiquitination PhosphoSitePlus
S125 Phosphorylation PhosphoSitePlus
K132 Ubiquitination PhosphoSitePlus
K136 Ubiquitination PhosphoSitePlus
K148 Acetylation PhosphoSitePlus
K148 Ubiquitination PhosphoSitePlus
K155 Ubiquitination PhosphoSitePlus
R169 Methylation PhosphoSitePlus
T189 Phosphorylation HPRD   PhosphoSitePlus 20068231
K193 Ubiquitination PhosphoSitePlus
K224 Ubiquitination PhosphoSitePlus
K229 Ubiquitination PhosphoSitePlus
K250 Methylation PhosphoSitePlus
K250 Sumoylation PhosphoSitePlus
K250 Ubiquitination PhosphoSitePlus
S265 Phosphorylation PhosphoSitePlus
R268 Methylation PhosphoSitePlus
K286 Sumoylation PhosphoSitePlus
K286 Ubiquitination PhosphoSitePlus
Y291 Phosphorylation PhosphoSitePlus
K294 Acetylation PhosphoSitePlus   UniProt 19608861
K294 Sumoylation PhosphoSitePlus
K294 Ubiquitination PhosphoSitePlus
K297 Ubiquitination PhosphoSitePlus
K300 Sumoylation PhosphoSitePlus
K300 Ubiquitination PhosphoSitePlus
S304 Phosphorylation PhosphoSitePlus   UniProt 21406692
T305 Phosphorylation PhosphoSitePlus
Y307 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18083107
S310 Phosphorylation PhosphoSitePlus
K312 Sumoylation PhosphoSitePlus
K312 Ubiquitination PhosphoSitePlus
K341 Acetylation PhosphoSitePlus
K341 Ubiquitination PhosphoSitePlus
K342 Acetylation PhosphoSitePlus
K349 Ubiquitination PhosphoSitePlus
S350 Phosphorylation PhosphoSitePlus
K356 Ubiquitination PhosphoSitePlus
K362 Acetylation PhosphoSitePlus
K362 Ubiquitination PhosphoSitePlus
K366 Acetylation PhosphoSitePlus   UniProt 19608861
K366 Sumoylation PhosphoSitePlus
K366 Ubiquitination PhosphoSitePlus
K373 Acetylation PhosphoSitePlus
K373 Methylation PhosphoSitePlus
K373 Sumoylation PhosphoSitePlus
K373 Ubiquitination PhosphoSitePlus
T381 Phosphorylation HPRD   PhosphoSitePlus 20068231
K385 Ubiquitination PhosphoSitePlus
K386 Sumoylation PhosphoSitePlus
K386 Ubiquitination PhosphoSitePlus
K393 Acetylation PhosphoSitePlus
K393 Sumoylation PhosphoSitePlus
K393 Ubiquitination PhosphoSitePlus
K394 Methylation PhosphoSitePlus
K399 Methylation PhosphoSitePlus
K399 Sumoylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S13 P13 Biomuta DOID:363 / uterine cancer [ tcga ]
R19 G19 Biomuta DOID:5041 / esophageal cancer [ tcga ]
K39 N39 Biomuta DOID:263 / kidney cancer [ cosmic, icgc, tcga ]
K120 N120 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]
K136 T136 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ] DOID:1909 / melanoma [ cosmic ]
R169 C169 Biomuta DOID:363 / uterine cancer [ tcga ]
R268 S268 Biomuta DOID:3571 / liver cancer [ icgc ]
Y291 C291 Biomuta DOID:9256 / colorectal cancer [ icgc, tcga ]
K300 R300 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc ]
K356 T356 Biomuta DOID:3571 / liver cancer [ icgc ]
K362 N362 Biomuta DOID:4362 / cervical cancer [ cosmic, icgc, tcga ]
K393 N393 Biomuta DOID:2394 / ovarian cancer [ tcga ]