iPTMnet Report for P38935 (IGHMBP2)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P38935 / SMBP2_HUMAN
Protein Name DNA-binding protein SMUBP-2
Gene Name Name: IGHMBP2
Synonyms:SMBP2,SMUBP2;
Organism Homo sapiens (Human)

PRO ID PR:P38935
DAG View
PRO Name DNA-binding protein SMUBP-2 (human)
Definition A DNA-binding protein SMUBP-2 that is encoded in the genome of human.
Short Label hIGHMBP2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P38935 (IGHMBP2) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 22814378, 22223895
S36 Phosphorylation IEDB 35494241
K38 Ubiquitination PhosphoSitePlus
S85 Phosphorylation PhosphoSitePlus
Y92 Phosphorylation PhosphoSitePlus
K138 Ubiquitination PhosphoSitePlus
S160 Phosphorylation PhosphoSitePlus
T218 Phosphorylation PhosphoSitePlus
K237 Ubiquitination PhosphoSitePlus
K259 Ubiquitination PhosphoSitePlus
S289 Phosphorylation PhosphoSitePlus
K298 Ubiquitination PhosphoSitePlus
K306 Ubiquitination PhosphoSitePlus
K324 Ubiquitination PhosphoSitePlus
C385 Methylation IEDB 31844290
K394 Acetylation PhosphoSitePlus
K394 Ubiquitination PhosphoSitePlus
K402 Ubiquitination PhosphoSitePlus
Y430 Phosphorylation IEDB 35494241
S539 Phosphorylation PhosphoSitePlus
K572 Ubiquitination PhosphoSitePlus
S656 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 17525332
T675 Phosphorylation PhosphoSitePlus
S677 Phosphorylation PhosphoSitePlus
S711 Phosphorylation PhosphoSitePlus
S716 Phosphorylation HPRD   PhosphoSitePlus 20068231, 18452278
S722 Phosphorylation PhosphoSitePlus
S843 Phosphorylation PhosphoSitePlus
S945 Phosphorylation PhosphoSitePlus
Y951 Phosphorylation PhosphoSitePlus
S954 Phosphorylation PhosphoSitePlus
T956 Phosphorylation PhosphoSitePlus
S978 Phosphorylation PhosphoSitePlus
S986 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K237 Q237 Biomuta DOID:4159 / skin cancer [ cosmic ]
S289 T289 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S289 G289 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S677 G677 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S722 C722 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
Y951 C951 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S986 N986 Biomuta DOID:9256 / colorectal cancer [ cosmic ]