iPTMnet Report for P38606 (ATP6V1A)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P38606 / VATA_HUMAN
Protein Name V-type proton ATPase catalytic subunit A
Gene Name Name: ATP6V1A
Synonyms:ATP6A1,ATP6V1A1,VPP2;
Organism Homo sapiens (Human)

PRO ID PR:P38606
DAG View
PRO Name V-type proton ATPase catalytic subunit A (human)
Definition A V-type proton ATPase catalytic subunit A that is encoded in the genome of human.
Short Label hATP6V1A
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P38606 (ATP6V1A) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
D2 Acetylation UniProt 22814378
K5 Ubiquitination PhosphoSitePlus
K8 Ubiquitination PhosphoSitePlus
K84 Ubiquitination PhosphoSitePlus
Y117 Phosphorylation PhosphoSitePlus
S125 Phosphorylation PhosphoSitePlus
K132 Ubiquitination PhosphoSitePlus
T136 Phosphorylation PhosphoSitePlus   UniProt 23186163
K139 Ubiquitination PhosphoSitePlus
S145 Phosphorylation PhosphoSitePlus
T148 Phosphorylation PhosphoSitePlus
Y153 Phosphorylation PhosphoSitePlus
S160 Phosphorylation PhosphoSitePlus
K163 Ubiquitination PhosphoSitePlus
K165 Ubiquitination PhosphoSitePlus
T175 Phosphorylation neXtProt 20525692
K220 Ubiquitination PhosphoSitePlus
K256 Ubiquitination PhosphoSitePlus
T257 O-Glycosylation GlyGen 23301498, 35008409, 34229054, ...34725712, 30059200, 35254053, 31492838, 28657654, 29237092
S260 O-Glycosylation GlyGen 23301498, 35008409, 34229054, ...34725712, 30059200, 35254053, 31492838, 28657654, 29237092
K265 Methylation PhosphoSitePlus
K265 Ubiquitination PhosphoSitePlus
K307 Ubiquitination PhosphoSitePlus
T309 Phosphorylation PhosphoSitePlus
S316 Phosphorylation PhosphoSitePlus
R364 Methylation PhosphoSitePlus
R381 Methylation PhosphoSitePlus
S384 Phosphorylation PhosphoSitePlus   UniProt 23186163
K393 Ubiquitination PhosphoSitePlus
Y454 Phosphorylation PhosphoSitePlus
Y457 Phosphorylation PhosphoSitePlus
Y464 Phosphorylation PhosphoSitePlus
Y465 Phosphorylation PhosphoSitePlus
K467 Acetylation PhosphoSitePlus
K467 Ubiquitination PhosphoSitePlus
K480 Ubiquitination PhosphoSitePlus
K498 Ubiquitination PhosphoSitePlus
K506 Ubiquitination PhosphoSitePlus
K513 Ubiquitination PhosphoSitePlus
K516 Ubiquitination PhosphoSitePlus
Y528 Phosphorylation PhosphoSitePlus
R530 Methylation PhosphoSitePlus
C532 Methylation IEDB 31844290
K564 Ubiquitination PhosphoSitePlus
Y579 Phosphorylation PhosphoSitePlus
K580 Acetylation PhosphoSitePlus
K580 Ubiquitination PhosphoSitePlus
K585 Ubiquitination PhosphoSitePlus
K587 Ubiquitination PhosphoSitePlus
K591 Ubiquitination PhosphoSitePlus
K596 Acetylation PhosphoSitePlus
K598 Ubiquitination PhosphoSitePlus
S599 Phosphorylation PhosphoSitePlus
Y601 Phosphorylation PhosphoSitePlus
S614 Phosphorylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S145 Phosphorylation HPRD 20068231
T148 Phosphorylation HPRD 20068231
Y153 Phosphorylation HPRD 20068231
S157 Phosphorylation HPRD 20068231
S316 Phosphorylation HPRD 20068231


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K84 N84 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S160 W160 Biomuta DOID:263 / kidney cancer [ icgc ]
T175 N175 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
T309 K309 Biomuta DOID:3571 / liver cancer [ cosmic ]
S316 F316 Biomuta DOID:4159 / skin cancer [ cosmic ]
R364 C364 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S384 L384 Biomuta [ cosmic ]
Y465 C465 Biomuta DOID:9256 / colorectal cancer [ cosmic ] DOID:3571 / liver cancer [ cosmic ]
K480 N480 Biomuta DOID:363 / uterine cancer [ icgc ]
K506 N506 Biomuta DOID:1324 / lung cancer [ cosmic, icgc ]
K580 Q580 Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc ]
K587 N587 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ] DOID:1324 / lung cancer [ cosmic, icgc ]
K596 N596 Biomuta DOID:363 / uterine cancer [ icgc ]
K596 Q596 Biomuta DOID:1612 / breast cancer [ cosmic, icgc ]
S599 N599 Biomuta DOID:9256 / colorectal cancer [ cosmic ]