iPTMnet Report for P38571 (LIPA)
Protein Information
| UniProt AC / UniProt ID | P38571 / LICH_HUMAN |
| Protein Name | Lysosomal acid lipase/cholesteryl ester hydrolase precursor |
| Gene Name | Name: LIPA |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P38571 |
| PRO Name | lysosomal acid lipase/cholesteryl ester hydrolase (human) |
| Definition | A lysosomal acid lipase/cholesteryl ester hydrolase that is encoded in the genome of human. |
| Short Label | hLIPA |
| Category | organism-gene |
DAG ViewP38571 (LIPA) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| C11 | Methylation | score1 | IEDB | 31844290 | ||
| C62 | Methylation | score1 | IEDB | 31844290 | ||
| N119 | N-Glycosylation | score1 | GlyGen | 24190977 | ||
| N161 | N-Glycosylation | score2 | GlyGen UniProt | 29741879, 19159218, 24190977 | ||
| K231 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S237 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N273 | N-Glycosylation | score1 | GlyGen | 29741879 | ||
| K304 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y317 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y320 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N321 | N-Glycosylation | score2 | GlyGen UniProt | 29741879, 19159218, 24190977 | ||
| Y328 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| C62 | Y62 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
| N321 | H321 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] |
