Protein Information

Cytoscape View


UniProt AC / UniProt ID P38432 / COIL_HUMAN
Protein Name Coilin
Gene Name Name: COIL
Synonyms:CLN80;
Organism Homo sapiens (Human)

PRO ID PR:P38432
DAG View
PRO Name coilin (human)
Definition A coilin that is encoded in the genome of human.
Short Label hCOIL
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P38432 (COIL) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T39 Phosphorylation PhosphoSitePlus
S43 Phosphorylation PhosphoSitePlus
S94 Phosphorylation PhosphoSitePlus
S105 Phosphorylation HPRD   PhosphoSitePlus   UniProt 20068231
T122 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 21406692, 19691289, ...23186163, 16964243, 18767875, 19664994, 19664995, 16565220, 19651622, 18669648, 24275569, 17287340, 19415658, 20068231, 17081983
C126 S-Nitrosylation dbSNO 26338901
Y128 Phosphorylation PhosphoSitePlus
S129 Phosphorylation PhosphoSitePlus
K151 Sumoylation PhosphoSitePlus
K151 Ubiquitination PhosphoSitePlus
K160 Ubiquitination PhosphoSitePlus
T169 Phosphorylation PhosphoSitePlus
T172 Phosphorylation PhosphoSitePlus
S184 Phosphorylation P24941 (CDK2) , Q86Y07 (VRK2) , Q99986 (VRK1) HPRD   neXtProt   phospho.ELM   PhosphoSitePlus   RLIMS-P   Signor   UniProt 26068304, 11102515, 21920476
S202 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 9013710
K204 Acetylation PhosphoSitePlus
K209 Sumoylation PhosphoSitePlus
K209 Ubiquitination PhosphoSitePlus
S217 Phosphorylation PhosphoSitePlus
S218 Phosphorylation PhosphoSitePlus
S226 Phosphorylation PhosphoSitePlus
S235 Phosphorylation PhosphoSitePlus
S240 Phosphorylation PhosphoSitePlus
S247 Phosphorylation PhosphoSitePlus
S256 Phosphorylation PhosphoSitePlus
S271 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 21406692, 23186163, ...19691289, 18452278, 18669648, 20068231
S272 Phosphorylation HPRD   PhosphoSitePlus   UniProt 17081983, 20068231
K274 Ubiquitination PhosphoSitePlus
T277 Phosphorylation HPRD   PhosphoSitePlus 20068231
K281 Ubiquitination PhosphoSitePlus
T286 Phosphorylation PhosphoSitePlus
T289 Phosphorylation PhosphoSitePlus
T290 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648
K293 Acetylation PhosphoSitePlus
K293 Ubiquitination PhosphoSitePlus
S301 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163
T303 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 23186163, 20058876, ...15302935, 19664995, 19651622, 19664994, 18669648, 20068231
S305 Phosphorylation PhosphoSitePlus
R350 Methylation PhosphoSitePlus
R352 Methylation PhosphoSitePlus
R393 Methylation PhosphoSitePlus
R397 Methylation PhosphoSitePlus
S403 Phosphorylation HPRD   PhosphoSitePlus   UniProt 23186163, 20068231
K405 Acetylation PhosphoSitePlus
K405 Methylation PhosphoSitePlus
K405 Ubiquitination PhosphoSitePlus
R419 Methylation PhosphoSitePlus
S447 Phosphorylation PhosphoSitePlus
T448 Phosphorylation PhosphoSitePlus
T456 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19664995, ...20068231
K459 Ubiquitination PhosphoSitePlus
Y461 Phosphorylation PhosphoSitePlus
S462 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus 18669648
K476 Ubiquitination PhosphoSitePlus
S486 Phosphorylation HPRD   PhosphoSitePlus 18452278
S487 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 18669648, 23186163, ...18452278
Y488 Phosphorylation HPRD   PhosphoSitePlus 18452278
S489 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 19413330, 23186163, 16964243, ...21991343, 18452278, 19651622, 18669648, 23616925, 20068231
K496 Acetylation PhosphoSitePlus
K496 Ubiquitination PhosphoSitePlus
S502 Phosphorylation PhosphoSitePlus
K555 Ubiquitination PhosphoSitePlus
S566 Phosphorylation HPRD   phospho.ELM   PhosphoSitePlus   UniProt 19413330, 21406692, 23186163, ...19664995, 18452278, 19651622, 16565220, 20068231
S568 Phosphorylation HPRD   PhosphoSitePlus 19413330, 19651622, 18452278
T570 Phosphorylation HPRD 19651622
S571 Phosphorylation HPRD   PhosphoSitePlus 17081983
S572 Phosphorylation HPRD   PhosphoSitePlus 19651622, 17081983
T573 Phosphorylation HPRD   PhosphoSitePlus 17081983


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T169 A169 Biomuta DOID:9256 / colorectal cancer [ tcga ]
S226 N226 Biomuta DOID:363 / uterine cancer [ tcga ] DOID:0070003 / blastoma [ cosmic ]
S247 F247 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
R419 Q419 Biomuta DOID:4362 / cervical cancer [ icgc, tcga ]
R419 * Biomuta DOID:11054 / urinary bladder cancer [ cosmic, icgc, tcga ]
S447 C447 Biomuta DOID:11934 / head and neck cancer [ tcga ]
T448 A448 Biomuta DOID:1324 / lung cancer [ cosmic, icgc, tcga ]
T456 I456 Biomuta DOID:3963 / thyroid carcinoma [ cosmic ]
Y461 C461 Biomuta DOID:10283 / prostate cancer [ cosmic ]
S486 C486 Biomuta DOID:10283 / prostate cancer [ cosmic ]
Y488 * Biomuta DOID:1115 / sarcoma [ tcga ]
K555 E555 Biomuta DOID:3963 / thyroid carcinoma [ cosmic, icgc, tcga ] DOID:1115 / sarcoma [ tcga ]
S566 T566 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc, tcga ]
T570 K570 Biomuta DOID:3571 / liver cancer [ icgc ]