Protein Information

Cytoscape View

UniProt AC / UniProt ID P37802 / TAGL2_HUMAN
Protein Name Transgelin-2
Gene Name Name: TAGLN2
Organism Homo sapiens (Human)

PRO ID PR:P37802
DAG View
PRO Name transgelin-2 (human)
Definition A transgelin-2 that is encoded in the genome of human.
Short Label hTAGLN2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

P37802 (TAGLN2) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
A2 Acetylation UniProt 19413330
R4 Methylation PhosphoSitePlus
Y8 Phosphorylation PhosphoSitePlus
S11 Phosphorylation P17252 (PRKCA) PhosphoSitePlus   UniProt 25844069, 23186163
K17 Acetylation PhosphoSitePlus   UniProt 19608861
K17 Ubiquitination PhosphoSitePlus
K20 Acetylation PhosphoSitePlus   UniProt 19608861
K20 Ubiquitination PhosphoSitePlus
K40 Ubiquitination PhosphoSitePlus
K57 Sumoylation PhosphoSitePlus
T60 Phosphorylation PhosphoSitePlus
K78 Acetylation PhosphoSitePlus
K78 Ubiquitination PhosphoSitePlus
K79 Acetylation PhosphoSitePlus
K79 Sumoylation PhosphoSitePlus
K79 Ubiquitination PhosphoSitePlus
S83 Phosphorylation O94921 (CDK14) PhosphoSitePlus 21577206
T84 Phosphorylation PhosphoSitePlus   RLIMS-P 25844069
K88 Acetylation PhosphoSitePlus
K88 Ubiquitination PhosphoSitePlus
S94 Phosphorylation PhosphoSitePlus
T128 Phosphorylation PhosphoSitePlus
R139 Methylation PhosphoSitePlus
S145 Phosphorylation P28482 (MAPK1) PhosphoSitePlus   RLIMS-P   Signor 30041673
K153 Acetylation PhosphoSitePlus
K153 Ubiquitination PhosphoSitePlus
K154 Ubiquitination PhosphoSitePlus
K156 Ubiquitination PhosphoSitePlus
S163 Phosphorylation O94921 (CDK14) , P17612 (PRKACA) phospho.ELM   PhosphoSitePlus   RLIMS-P   UniProt 21406692, 23186163, 21577206, ...18669648, 18088087, 25844069, 19690332, 20068231
K171 Acetylation PhosphoSitePlus
K171 Sumoylation PhosphoSitePlus
K171 Ubiquitination PhosphoSitePlus
T180 Phosphorylation P17252 (PRKCA) PhosphoSitePlus   RLIMS-P   UniProt 23186163, 25844069
R182 Methylation PhosphoSitePlus   UniProt 24129315
S185 Phosphorylation P17252 (PRKCA) phospho.ELM   PhosphoSitePlus   RLIMS-P 18088087, 18669648, 25844069
T190 Phosphorylation PhosphoSitePlus
Y192 Phosphorylation phospho.ELM   PhosphoSitePlus 18083107
R196 Methylation PhosphoSitePlus   UniProt 24129315
Site PTM Type PTM Enzyme Score Source PMID
S163 Phosphorylation HPRD 19413330, 18088087, 18212344, ...18767875, 20058876, 19651622, 18669648, 20166139, 20068231
T180 Phosphorylation HPRD 18212344
S185 Phosphorylation HPRD 18669648, 18088087, 18212344
Y192 Phosphorylation HPRD 19901323

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
A2 T2 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]
K79 N79 Biomuta DOID:9256 / colorectal cancer [ tcga ] DOID:1909 / melanoma [ cosmic ]
S94 C94 Biomuta DOID:1324 / lung cancer [ tcga ]
K153 N153 Biomuta DOID:363 / uterine cancer [ tcga ]
R182 C182 Biomuta DOID:9256 / colorectal cancer [ tcga ]
Y192 * Biomuta DOID:3571 / liver cancer [ icgc ]
R196 C196 Biomuta DOID:1793 / pancreatic cancer [ tcga ]