Protein Information

Cytoscape View

UniProt AC / UniProt ID P37287 / PIGA_HUMAN
Protein Name Phosphatidylinositol N-acetylglucosaminyltransferase subunit A
Gene Name Name: PIGA
Organism Homo sapiens (Human)

PRO ID PR:P37287
DAG View
PRO Name phosphatidylinositol N-acetylglucosaminyltransferase subunit A (human)
Definition An N-acetylglucosaminyl-phosphatidylinositol biosynthetic protein that is encoded in the genome of human.
Short Label hPIGA
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

P37287 (PIGA) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
R4 Methylation PhosphoSitePlus
S21 Phosphorylation PhosphoSitePlus   UniProt 18691976, 23186163
S24 Phosphorylation PhosphoSitePlus   UniProt 23186163
T27 Phosphorylation PhosphoSitePlus
T32 Phosphorylation PhosphoSitePlus
Y254 Phosphorylation PhosphoSitePlus
K293 Ubiquitination PhosphoSitePlus
S354 Phosphorylation PhosphoSitePlus
K361 Ubiquitination PhosphoSitePlus
K367 Ubiquitination PhosphoSitePlus
Y385 Phosphorylation PhosphoSitePlus
K396 Acetylation PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
S21 Phosphorylation HPRD 18691976

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S24 R24 Biomuta DOID:3571 / liver cancer [ icgc ] DOID:0070003 / blastoma [ cosmic ]
T32 N32 Biomuta DOID:3571 / liver cancer [ icgc ]
K361 R361 Biomuta DOID:3277 / thymus cancer [ tcga ]
K361 N361 Biomuta DOID:1324 / lung cancer [ tcga ]