iPTMnet Report for P37287 (PIGA)
Protein Information
UniProt AC / UniProt ID | P37287 / PIGA_HUMAN |
Protein Name | Phosphatidylinositol N-acetylglucosaminyltransferase subunit A |
Gene Name | Name: PIGA |
Organism | Homo sapiens (Human) |
PRO ID | PR:P37287 |
PRO Name | phosphatidylinositol N-acetylglucosaminyltransferase subunit A (human) |
Definition | An N-acetylglucosaminyl-phosphatidylinositol biosynthetic protein that is encoded in the genome of human. |
Short Label | hPIGA |
Category | organism-gene |
P37287 (PIGA) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
R4 | Methylation | score1 | PhosphoSitePlus | |||
S21 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 18691976, 23186163 | ||
S24 | Phosphorylation | score2 | PhosphoSitePlus UniProt | 23186163 | ||
T27 | Phosphorylation | score1 | PhosphoSitePlus | |||
T32 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y254 | Phosphorylation | score1 | PhosphoSitePlus | |||
K293 | Ubiquitination | score1 | PhosphoSitePlus | |||
S354 | Phosphorylation | score1 | PhosphoSitePlus | |||
K361 | Ubiquitination | score1 | PhosphoSitePlus | |||
K367 | Ubiquitination | score1 | PhosphoSitePlus | |||
Y385 | Phosphorylation | score1 | PhosphoSitePlus | |||
K396 | Acetylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
S24 | R24 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
Y254 | C254 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
K361 | N361 | Biomuta | DOID:1324 / lung cancer [ cosmic ] |