Protein Information

Cytoscape View


UniProt AC / UniProt ID P37058 / DHB3_HUMAN
Protein Name 17-beta-hydroxysteroid dehydrogenase type 3
Gene Name Name: HSD17B3
Synonyms:EDH17B3,SDR12C2;
Organism Homo sapiens (Human)

PRO ID PR:P37058
DAG View
PRO Name 17-beta-hydroxysteroid dehydrogenase type 3 (human)
Definition A 17-beta-hydroxysteroid dehydrogenase type 3 that is encoded in the genome of human.
Short Label hHSD17B3
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P37058 (HSD17B3) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S174 Phosphorylation PhosphoSitePlus
S185 Phosphorylation PhosphoSitePlus
S196 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S174 * Biomuta DOID:1324 / lung cancer [ cosmic ]
S185 F185 Biomuta DOID:4159 / skin cancer [ cosmic ] DOID:1781 / thyroid gland cancer [ cosmic ]