iPTMnet Report for P37023 (ACVRL1)
Protein Information
| UniProt AC / UniProt ID | P37023 / ACVL1_HUMAN |
| Protein Name | Serine/threonine-protein kinase receptor R3 precursor |
| Gene Name | Name: ACVRL1 Synonyms:ACVRLK1,ALK1; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P37023 |
| PRO Name | serine/threonine-protein kinase receptor R3 (human) |
| Definition | A serine/threonine-protein kinase receptor R3 that is encoded in the genome of human. |
| Short Label | hACVRL1 |
| Category | organism-gene |
DAG ViewP37023 (ACVRL1) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S160 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S161 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y375 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T412 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y421 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K439 | Acetylation | score1 | PhosphoSitePlus | |||
| K440 | Acetylation | score1 | PhosphoSitePlus |
P37023 (ACVRL1) as PTM Enzyme
|
Substrate | Site | Score | Source | PMID |
|---|---|---|---|---|---|
| P17813 (ENG) | T640 | score2 | PhosphoSitePlus | 16785228 | |
| P17813 (ENG) | S646 | score2 | PhosphoSitePlus | 20042635 | |
| P17813 (ENG) | S649 | score2 | PhosphoSitePlus | 20042635 | |
| P17813 (ENG) | T654 | score2 | PhosphoSitePlus | 16785228 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| Y421 | C421 | Biomuta | DOID:11054 / urinary bladder cancer [ cosmic, icgc ] |
 |