iPTMnet Report for P36959 (GMPR)
Protein Information
| UniProt AC / UniProt ID | P36959 / GMPR1_HUMAN |
| Protein Name | GMP reductase 1 |
| Gene Name | Name: GMPR Synonyms:GMPR1; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P36959 |
| PRO Name | GMP reductase 1 (human) |
| Definition | A GMP reductase 1 that is encoded in the genome of human. |
| Short Label | hGMPR |
| Category | organism-gene |
DAG ViewP36959 (GMPR) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| K13 | Acetylation | score1 | PhosphoSitePlus | |||
| K13 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K20 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T37 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S81 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y267 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 35148834 | ||
| S270 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S271 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T273 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y318 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T332 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S345 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| T37 | M37 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:9256 / colorectal cancer [ cosmic, icgc ] | |
| S270 | N270 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| T273 | I273 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] |
