Protein Information

Cytoscape View


UniProt AC / UniProt ID P36955 / PEDF_HUMAN
Protein Name Pigment epithelium-derived factor precursor
Gene Name Name: SERPINF1
Synonyms:PEDF;ORFNames:PIG35;
Organism Homo sapiens (Human)

PRO ID PR:P36955
DAG View
PRO Name pigment epithelium-derived factor (human)
Definition A pigment epithelium-derived factor that is encoded in the genome of human.
Short Label hSERPINF1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P36955 (SERPINF1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S24 O-Glycosylation GlyGen 30459171
S24 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus   RLIMS-P   UniProt 15374885
S30 O-Glycosylation GlyGen 30459171
T36 O-Glycosylation GlyGen 30459171
S114 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus   RLIMS-P   UniProt 15374885
S152 Phosphorylation PhosphoSitePlus
S153 Phosphorylation PhosphoSitePlus
T170 Phosphorylation IEDB 35494241
S227 Phosphorylation P17612 (PRKACA) PhosphoSitePlus   UniProt 15374885
T283 Phosphorylation PhosphoSitePlus
N285 N-Glycosylation GlyGen   UniProt 16335952, 19159218, 29391424, ...19139490, 24279413, 11562499, 29741879
T287 Phosphorylation PhosphoSitePlus
T294 Phosphorylation PhosphoSitePlus
S295 Phosphorylation PhosphoSitePlus
K316 Methylation PhosphoSitePlus
T372 O-Glycosylation GlyGen 30459171
S374 O-Glycosylation GlyGen 30459171


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S114 N114 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4362 / cervical cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic ]
S152 T152 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S152 F152 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S153 R153 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]