Protein Information

Cytoscape View


UniProt AC / UniProt ID P36955 / PEDF_HUMAN
Protein Name Pigment epithelium-derived factor precursor
Gene Name Name: SERPINF1
Synonyms:PEDF;ORFNames:PIG35;
Organism Homo sapiens (Human)

PRO ID PR:P36955
DAG View
PRO Name pigment epithelium-derived factor (human)
Definition A pigment epithelium-derived factor that is encoded in the genome of human.
Short Label hSERPINF1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P36955 (SERPINF1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S24 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus   RLIMS-P   UniProt 15374885
S114 Phosphorylation P68400 (CSNK2A1) PhosphoSitePlus   RLIMS-P   UniProt 15374885
S152 Phosphorylation PhosphoSitePlus
S153 Phosphorylation PhosphoSitePlus
S227 Phosphorylation P17612 (PRKACA) PhosphoSitePlus   UniProt 15374885
T283 Phosphorylation PhosphoSitePlus
N285 N-Glycosylation UniProt 16335952, 19139490, 19159218, ...11562499
T287 Phosphorylation PhosphoSitePlus
T294 Phosphorylation PhosphoSitePlus
S295 Phosphorylation PhosphoSitePlus
K316 Methylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S114 N114 Biomuta DOID:363 / uterine cancer [ tcga ] DOID:4362 / cervical cancer [ tcga ] DOID:1909 / melanoma [ cosmic ] DOID:9256 / colorectal cancer [ tcga ]
S152 T152 Biomuta DOID:2394 / ovarian cancer [ icgc ] DOID:2994 / germ cell cancer [ cosmic ]
S152 F152 Biomuta DOID:2394 / ovarian cancer [ icgc ] DOID:2994 / germ cell cancer [ cosmic ]