iPTMnet Report for P36955 (SERPINF1)
Protein Information
| UniProt AC / UniProt ID | P36955 / PEDF_HUMAN |
| Protein Name | Pigment epithelium-derived factor precursor |
| Gene Name | Name: SERPINF1 Synonyms:PEDF;ORFNames:PIG35; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P36955 |
| PRO Name | pigment epithelium-derived factor (human) |
| Definition | A pigment epithelium-derived factor that is encoded in the genome of human. |
| Short Label | hSERPINF1 |
| Category | organism-gene |
P36955 (SERPINF1) as Substrate
| Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
|---|---|---|---|---|---|---|
| S24 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| S24 | Phosphorylation | P68400 (CSNK2A1) | score3 | PhosphoSitePlus RLIMS-P UniProt | 15374885 | |
| S30 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| T36 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| S114 | Phosphorylation | P68400 (CSNK2A1) | score3 | PhosphoSitePlus RLIMS-P UniProt | 15374885 | |
| S152 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S153 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T170 | Phosphorylation | score1 | IEDB | 35494241 | ||
| S227 | Phosphorylation | P17612 (PRKACA) | score3 | PhosphoSitePlus UniProt | 15374885 | |
| T283 | Phosphorylation | score1 | PhosphoSitePlus | |||
| N285 | N-Glycosylation | score4 | GlyGen UniProt | 16335952, 19159218, 29391424, ... | ||
| T287 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T294 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S295 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K316 | Methylation | score1 | PhosphoSitePlus | |||
| T372 | O-Glycosylation | score1 | GlyGen | 30459171 | ||
| S374 | O-Glycosylation | score1 | GlyGen | 30459171 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S114 | N114 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] DOID:4362 / cervical cancer [ icgc ] DOID:9256 / colorectal cancer [ cosmic ] | |
| S152 | T152 | Biomuta | DOID:2394 / ovarian cancer [ cosmic, icgc ] | |
| S152 | F152 | Biomuta | DOID:2394 / ovarian cancer [ cosmic, icgc ] | |
| S153 | R153 | Biomuta | DOID:4159 / skin cancer [ cosmic, icgc ] |
DAG View