iPTMnet Report for P36952 (SERPINB5)
Protein Information
| UniProt AC / UniProt ID | P36952 / SPB5_HUMAN |
| Protein Name | Serpin B5 |
| Gene Name | Name: SERPINB5 Synonyms:PI5; |
| Organism | Homo sapiens (Human) |
| PRO ID | PR:P36952 |
| PRO Name | serpin B5 (human) |
| Definition | A serpin B5 that is encoded in the genome of human. |
| Short Label | hSERPINB5 |
| Category | organism-gene |
DAG ViewP36952 (SERPINB5) as Substrate
 |
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S9 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T50 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 21365746 | ||
| K64 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K79 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S85 | Phosphorylation | score1 | PhosphoSitePlus | |||
| Y93 | Phosphorylation | score1 | PhosphoSitePlus | |||
| S97 | O-Glycosylation | score1 | GlyGen | 33465208, 30397120 | ||
| S97 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 21365746 | ||
| K109 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K114 | Acetylation | score1 | PhosphoSitePlus | |||
| K114 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T118 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 21365746 | ||
| K122 | Acetylation | score1 | PhosphoSitePlus | |||
| K129 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S135 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K137 | Ubiquitination | score1 | PhosphoSitePlus | |||
| T157 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 21365746 | ||
| S240 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 21365746 | ||
| T241 | Phosphorylation | score1 | PhosphoSitePlus | |||
| K245 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K248 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K275 | Ubiquitination | score1 | PhosphoSitePlus | |||
| K277 | Acetylation | score1 | PhosphoSitePlus | |||
| K280 | Acetylation | score1 | PhosphoSitePlus | |||
| K285 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S298 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 21365746 | ||
| S302 | Phosphorylation | score1 | PhosphoSitePlus | |||
| T310 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 21365746 | ||
| K311 | Ubiquitination | score1 | PhosphoSitePlus | |||
| S316 | Phosphorylation | score3 | PhosphoSitePlus RLIMS-P | 21365746 | ||
| K345 | Ubiquitination | score1 | PhosphoSitePlus | |||
| Y356 | Phosphorylation | score1 | PhosphoSitePlus |
|
Site | PTM Type | PTM Enzyme | Score | Source | PMID |
|---|---|---|---|---|---|---|
| S9 | Phosphorylation | score0 | HPRD | 20068231 | ||
| T102 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S106 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S107 | Phosphorylation | score0 | HPRD | 20068231 | ||
| T108 | Phosphorylation | score0 | HPRD | 20068231 | ||
| S135 | Phosphorylation | score0 | HPRD | 20068231 | ||
| Y356 | Phosphorylation | score0 | HPRD | 20068231 |
PTM sites affected in variants
| Site | Variant | Source | PMID | Disease [Sample source] |
|---|---|---|---|---|
| S9 | L9 | Biomuta | DOID:1785 / pituitary cancer [ cosmic ] DOID:11054 / urinary bladder cancer [ cosmic, icgc ] | |
| T108 | M108 | Biomuta | DOID:9256 / colorectal cancer [ cosmic ] | |
| T118 | P118 | Biomuta | DOID:363 / uterine cancer [ icgc ] | |
| S298 | R298 | Biomuta | DOID:363 / uterine cancer [ cosmic, icgc ] | |
| S316 | * | Biomuta | DOID:1324 / lung cancer [ cosmic ] |
