Protein Information

Cytoscape View


UniProt AC / UniProt ID P36915 / GNL1_HUMAN
Protein Name Guanine nucleotide-binding protein-like 1
Gene Name Name: GNL1
Synonyms:HSR1;
Organism Homo sapiens (Human)

PRO ID PR:P36915
DAG View
PRO Name guanine nucleotide-binding protein-like 1 (human)
Definition A guanine nucleotide-binding protein-like 1 that is encoded in the genome of human.
Short Label hGNL1
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P36915 (GNL1) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
S8 Phosphorylation PhosphoSitePlus
S32 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S33 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S34 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S36 Phosphorylation PhosphoSitePlus
T48 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 17081983, 18669648, ...24275569, 19690332
T50 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 23186163, 19690332, ...24275569
S51 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 23186163, 18220336, 18669648, ...24275569, 19690332
S55 Phosphorylation PhosphoSitePlus
T57 Phosphorylation PhosphoSitePlus
S68 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 17525332, 23186163
R74 Methylation PhosphoSitePlus
Y76 Phosphorylation PhosphoSitePlus
Y81 Phosphorylation PhosphoSitePlus
R82 Methylation PhosphoSitePlus
S89 Phosphorylation PhosphoSitePlus
S136 Phosphorylation PhosphoSitePlus
Y137 Phosphorylation PhosphoSitePlus
K141 Ubiquitination PhosphoSitePlus
Y155 Phosphorylation PhosphoSitePlus
K158 Ubiquitination PhosphoSitePlus
T282 Phosphorylation PhosphoSitePlus
K301 Ubiquitination PhosphoSitePlus
T319 Phosphorylation phospho.ELM 18669648
S324 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648, 21406692
K357 Ubiquitination PhosphoSitePlus
Y488 Phosphorylation PhosphoSitePlus
Y499 Phosphorylation PhosphoSitePlus
S561 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S562 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S563 Phosphorylation phospho.ELM   PhosphoSitePlus   UniProt 18669648
S587 Phosphorylation PhosphoSitePlus
Y599 Phosphorylation PhosphoSitePlus
C607 S-Nitrosylation dbSNO 26338901
Site PTM Type PTM Enzyme Score Source PMID
S32 Phosphorylation HPRD 19651622, 18669648
S33 Phosphorylation HPRD 19651622, 18669648
S34 Phosphorylation HPRD 19651622, 18669648
T48 Phosphorylation HPRD 19651622, 18669648, 20068231
T50 Phosphorylation HPRD 19651622, 20166139, 18669648, ...17081983, 20068231
S51 Phosphorylation HPRD 17081983, 18767875, 19651622, ...18669648, 18707149, 20166139, 20068231
S55 Phosphorylation HPRD 17081983
T57 Phosphorylation HPRD 17081983
S68 Phosphorylation HPRD 17525332
T319 Phosphorylation HPRD 18669648
S324 Phosphorylation HPRD 18669648, 18452278
S561 Phosphorylation HPRD 18669648
S562 Phosphorylation HPRD 18669648
S563 Phosphorylation HPRD 18669648


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S8 I8 Biomuta DOID:4159 / skin cancer [ cosmic ]
S33 N33 Biomuta DOID:2531 / hematologic cancer [ cosmic ]
S136 C136 Biomuta DOID:263 / kidney cancer [ cosmic, icgc ]
K141 R141 Biomuta DOID:10283 / prostate cancer [ cosmic, icgc ]
T319 P319 Biomuta DOID:263 / kidney cancer [ cosmic ]
K357 N357 Biomuta DOID:8618 / oral cavity cancer [ cosmic ]
S563 P563 Biomuta DOID:2394 / ovarian cancer [ cosmic, icgc ]
S587 L587 Biomuta DOID:10534 / stomach cancer [ cosmic ]