Protein Information

Cytoscape View

UniProt AC / UniProt ID P36551 / HEM6_HUMAN
Protein Name Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial precursor
Gene Name Name: CPOX
Organism Homo sapiens (Human)

PRO ID PR:P36551
DAG View
PRO Name oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial (human)
Definition An oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial that is encoded in the genome of human.
Short Label hCPOX
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

P36551 (CPOX) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
S112 Phosphorylation PhosphoSitePlus
K184 Ubiquitination PhosphoSitePlus
K220 Ubiquitination PhosphoSitePlus
R298 Methylation PhosphoSitePlus
K301 Ubiquitination PhosphoSitePlus
K314 Ubiquitination PhosphoSitePlus
K347 Ubiquitination PhosphoSitePlus
S356 Phosphorylation PhosphoSitePlus
K370 Ubiquitination PhosphoSitePlus
K404 Acetylation PhosphoSitePlus
K404 Ubiquitination PhosphoSitePlus
T409 Phosphorylation PhosphoSitePlus
S416 Phosphorylation PhosphoSitePlus
S420 Phosphorylation PhosphoSitePlus
T424 Phosphorylation PhosphoSitePlus
K438 Ubiquitination PhosphoSitePlus
Site PTM Type PTM Enzyme Score Source PMID
T424 Phosphorylation HPRD 20068231

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
K314 T314 Biomuta DOID:1793 / pancreatic cancer [ tcga ]
S356 R356 Biomuta DOID:363 / uterine cancer [ cosmic, icgc, tcga ]