iPTMnet Report for P36406 (TRIM23)
Protein Information
UniProt AC / UniProt ID | P36406 / TRI23_HUMAN |
Protein Name | E3 ubiquitin-protein ligase TRIM23 |
Gene Name | Name: TRIM23 Synonyms:ARD1,ARFD1,RNF46; |
Organism | Homo sapiens (Human) |
PRO ID | PR:P36406 |
PRO Name | E3 ubiquitin-protein ligase TRIM23 (human) |
Definition | An E3 ubiquitin-protein ligase TRIM23 that is encoded in the genome of human. |
Short Label | hTRIM23 |
Category | organism-gene |
P36406 (TRIM23) as Substrate
Site | PTM Type | PTM Enzyme | Score | Source | PMID | |
---|---|---|---|---|---|---|
K8 | Ubiquitination | score1 | PhosphoSitePlus | |||
S15 | Phosphorylation | score1 | PhosphoSitePlus | |||
S20 | Phosphorylation | score1 | PhosphoSitePlus | |||
K171 | Ubiquitination | score1 | PhosphoSitePlus | |||
K357 | Ubiquitination | score1 | PhosphoSitePlus | |||
S386 | Phosphorylation | score1 | PhosphoSitePlus | |||
K458 | Acetylation | score1 | PhosphoSitePlus | |||
Y468 | Phosphorylation | score1 | PhosphoSitePlus | |||
Y469 | Phosphorylation | score1 | PhosphoSitePlus | |||
K501 | Ubiquitination | score1 | PhosphoSitePlus | |||
S550 | Phosphorylation | score1 | PhosphoSitePlus |
PTM sites affected in variants
Site | Variant | Source | PMID | Disease [Sample source] |
---|---|---|---|---|
K8 | R8 | Biomuta | DOID:4606 / bile duct cancer [ cosmic ] | |
S15 | C15 | Biomuta | DOID:3571 / liver cancer [ cosmic ] | |
S386 | N386 | Biomuta | DOID:9253 / gastrointestinal stromal tumor [ cosmic ] | |
K458 | N458 | Biomuta | DOID:10534 / stomach cancer [ cosmic, icgc ] | |
Y469 | H469 | Biomuta | DOID:5158 / pleural cancer [ cosmic ] |