iPTMnet Report for P35869 (AHR)


Protein Information

Cytoscape View


UniProt AC / UniProt ID P35869 / AHR_HUMAN
Protein Name Aryl hydrocarbon receptor precursor
Gene Name Name: AHR
Synonyms:BHLHE76;
Organism Homo sapiens (Human)

PRO ID PR:P35869
DAG View
PRO Name aryl hydrocarbon receptor (human)
Definition An aryl hydrocarbon receptor that is encoded in the genome of human.
Short Label hAHR
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


P35869 (AHR) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
M1 Acetylation UniProt 22814378
S12 Phosphorylation P17252 (PRKCA) phospho.ELM   PhosphoSitePlus 15063792
K24 Acetylation PhosphoSitePlus
K24 Sumoylation PhosphoSitePlus
K24 Ubiquitination PhosphoSitePlus
K32 Ubiquitination PhosphoSitePlus
S36 Phosphorylation P17252 (PRKCA) phospho.ELM   PhosphoSitePlus 15063792
T45 Phosphorylation PhosphoSitePlus
K63 Ubiquitination PhosphoSitePlus
S68 Phosphorylation phospho.ELM   PhosphoSitePlus 14985336
S75 Phosphorylation PhosphoSitePlus
Y76 Phosphorylation PhosphoSitePlus
S81 Phosphorylation PhosphoSitePlus
K88 Ubiquitination PhosphoSitePlus
C101 Methylation IEDB 31844290
S232 Phosphorylation PhosphoSitePlus
K244 Ubiquitination PhosphoSitePlus
Y245 Phosphorylation PhosphoSitePlus
K254 Sumoylation PhosphoSitePlus
K292 Ubiquitination PhosphoSitePlus
Y322 Phosphorylation PhosphoSitePlus
T355 Phosphorylation PhosphoSitePlus
Y378 Phosphorylation HPRD   phospho.ELM 11032419
S436 Phosphorylation PhosphoSitePlus
K438 Ubiquitination PhosphoSitePlus
S440 Phosphorylation PhosphoSitePlus
S444 Phosphorylation PhosphoSitePlus
K510 Ubiquitination PhosphoSitePlus
K535 Ubiquitination PhosphoSitePlus
Y540 Phosphorylation PhosphoSitePlus
K544 Ubiquitination PhosphoSitePlus
K560 Ubiquitination PhosphoSitePlus
K641 Ubiquitination PhosphoSitePlus
S689 Phosphorylation PhosphoSitePlus
S693 Phosphorylation PhosphoSitePlus
T697 Phosphorylation PhosphoSitePlus
S723 Phosphorylation PhosphoSitePlus
S727 Phosphorylation PhosphoSitePlus
T731 Phosphorylation PhosphoSitePlus
C764 Methylation IEDB 31844290


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S81 C81 Biomuta DOID:10534 / stomach cancer [ cosmic, icgc ]
S232 Y232 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]
K244 * Biomuta DOID:1319 / brain cancer [ cosmic ]
Y245 C245 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
Y378 H378 Biomuta DOID:9256 / colorectal cancer [ cosmic ]
S440 Y440 Biomuta DOID:1319 / brain cancer [ icgc ]
K535 E535 Biomuta DOID:3571 / liver cancer [ cosmic ]
K560 T560 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
S689 F689 Biomuta DOID:4159 / skin cancer [ cosmic ]
S693 Y693 Biomuta DOID:363 / uterine cancer [ cosmic, icgc ]
C764 W764 Biomuta DOID:4159 / skin cancer [ cosmic, icgc ]